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Study Description

The study cohort comprises samples from patients whose tumors have been prospectively characterized as part of their care at Memorial Sloan Kettering Cancer Center. This includes a variety of distinct tumor type and molecular subtypes.

Authorized Access
Publicly Available Data
Study Inclusion/Exclusion Criteria

DNA samples from tumor tissue were from patients at Memorial Sloan Kettering Cancer Center. Tumor and normal sample libraries prepared for targeted MSK-IMPACT sequencing were recaptured for exome sequencing. Study participants were not selected on the basis of tumor type, molecular features of their tumor, or treatments.

Selected Publications
Diseases/Traits Related to Study (MeSH terms)
Authorized Data Access Requests
Study Attribution
  • Principal Investigator
    • David B. Solit. Memorial Sloan Kettering Cancer Center, NY, USA.
  • Investigators
    • Barry S. Taylor. Memorial Sloan Kettering Cancer Center, NY, USA.
    • Alexander E. Drilon. Memorial Sloan Kettering Cancer Center, NY, USA.
    • Ezra Y. Rosen. Memorial Sloan Kettering Cancer Center, NY, USA.
    • Sandra D’Angelo. Memorial Sloan Kettering Cancer Center, NY, USA.
    • Hikmat Al-Ahmadie. Memorial Sloan Kettering Cancer Center, NY, USA.
  • Funding Sources
    • U54 OD020355. National Institutes of Health, Bethesda, MD, USA.
    • P01 CA221757. National Institutes of Health, Bethesda, MD, USA.
    • R01 CA207244. National Institutes of Health, Bethesda, MD, USA.
    • P50 CA092629. National Institutes of Health, Bethesda, MD, USA.
    • R01 CA251591-01A1. National Institutes of Health, Bethesda, MD, USA.
    • 2T32 CA009512-29A1. National Institutes of Health, Bethesda, MD, USA.
    • I10-0084. Starr Cancer Consortium.
    • 1P50CA217694-01A1. National Cancer Institute (NCI), Bethesda, MD, USA.
    • R01CA233899. National Cancer Institute (NCI), Bethesda, MD, USA.
    • P01CA221757. National Cancer Institute (NCI), Bethesda, MD, USA.
    • P50CA221745. National Cancer Institute (NCI), Bethesda, MD, USA.
    • UL1-TR002384. National Center for Advancing Translational Sciences (NCATS), Bethesda, MD, USA.
    • P30-CA008748. National Cancer Institute (NCI), Bethesda, MD, USA.