Trends in HIV postexposure prophylaxis prescription and compliance after sexual exposure in Amsterdam, 2000-2004
- PMID: 16980918
- DOI: 10.1097/01.olq.0000237838.43716.ee
Trends in HIV postexposure prophylaxis prescription and compliance after sexual exposure in Amsterdam, 2000-2004
Abstract
Objective: The objective of this study was to evaluate trends in HIV postexposure prophylaxis (PEP) requests after sexual exposure, compliance, and outcome of follow-up HIV tests.
Study design: The authors conducted a retrospective analysis of all HIV PEP requests after sexual exposure between January 1, 2000, and December 31, 2004, in Amsterdam.
Results: In 5 years, there was a very modest increase in PEP requests, of which most (75%) came from men who have sex with men (MSM). Although 70% reported side effects, 85% completed their PEP course. Sexual assault victims less often completed their course (odds ratio [OR] = 0.1; 95% confidence interval [CI] = 0.05-0.4, P = 0.001). People who used HIV PEP more often complied with follow-up tests than people who did not use PEP (OR = 3.5; 95% CI = 1.6-7.9, P = 0.002). One HIV seroconversion was found caused by a later exposure than that for which PEP was given.
Conclusions: Despite a widely available PEP program in Amsterdam, the number of PEP requests remained low. Most people completed their PEP course; compliance with follow-up HIV testing was high.
Comment in
-
A model for communitywide delivery of postexposure prophylaxis after potential sexual exposure to HIV.Sex Transm Dis. 2007 May;34(5):294-6. doi: 10.1097/01.olq.0000258321.62272.0e. Sex Transm Dis. 2007. PMID: 17308501 No abstract available.
Similar articles
-
Use of human immunodeficiency virus postexposure prophylaxis in adolescent sexual assault victims.Arch Pediatr Adolesc Med. 2006 Jul;160(7):674-80. doi: 10.1001/archpedi.160.7.674. Arch Pediatr Adolesc Med. 2006. PMID: 16818831
-
HIV postexposure prophylaxis use among Ontario female adolescent sexual assault victims: a prospective analysis.Sex Transm Dis. 2008 Dec;35(12):973-8. doi: 10.1097/OLQ.0b013e3181824f3c. Sex Transm Dis. 2008. PMID: 18836390
-
The Danish PEP registry: experience with the use of postexposure prophylaxis (PEP) following sexual exposure to HIV from 1998 to 2006.Sex Transm Dis. 2010 Jan;37(1):49-52. doi: 10.1097/OLQ.0b013e3181b6f284. Sex Transm Dis. 2010. PMID: 19734819
-
Postexposure prophylaxis after sexual exposure to HIV.Curr Opin Infect Dis. 2007 Feb;20(1):39-46. doi: 10.1097/QCO.0b013e328012c5e0. Curr Opin Infect Dis. 2007. PMID: 17197880 Review.
-
Postexposure prophylaxis for HIV following sexual exposure.Curr Opin HIV AIDS. 2010 Jul;5(4):322-6. doi: 10.1097/COH.0b013e32833a5e6c. Curr Opin HIV AIDS. 2010. PMID: 20543608 Review.
Cited by
-
Concordance of emergency department physicians' decisions on HIV post-exposure prophylaxis with national guidelines: results from a retrospective cohort study.Int Health. 2024 Mar 4;16(2):219-226. doi: 10.1093/inthealth/ihad076. Int Health. 2024. PMID: 37624102 Free PMC article.
-
PrEP Scale-Up and PEP in Central and Eastern Europe: Changes in Time and the Challenges We Face with No Expected HIV Vaccine in the near Future.Vaccines (Basel). 2023 Jan 4;11(1):122. doi: 10.3390/vaccines11010122. Vaccines (Basel). 2023. PMID: 36679967 Free PMC article.
-
Suspected unexpected and other adverse reactions to antiretroviral drugs used as post-exposure prophylaxis of HIV infection - five-year experience from clinical practice.Arch Med Sci. 2018 Apr;14(3):547-553. doi: 10.5114/aoms.2016.59701. Epub 2016 May 5. Arch Med Sci. 2018. PMID: 29765441 Free PMC article.
-
Longitudinal trends in HIV nonoccupational postexposure prophylaxis use at a Boston community health center between 1997 and 2013.J Acquir Immune Defic Syndr. 2015 Jan 1;68(1):97-101. doi: 10.1097/QAI.0000000000000403. J Acquir Immune Defic Syndr. 2015. PMID: 25321180 Free PMC article.
-
Non-occupational post-exposure prophylaxis for HIV: 10-year retrospective analysis in Seattle, Washington.PLoS One. 2014 Aug 20;9(8):e105030. doi: 10.1371/journal.pone.0105030. eCollection 2014. PLoS One. 2014. PMID: 25140868 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous