Importance More than half of youth with autism spectrum disorders (ASDs) have sensory
overresponsivity (SOR), an extreme negative reaction to sensory stimuli. However, little is
known about the neurobiological basis of SOR, and there are few effective treatments.
Understanding whether SOR is due to an initial heightened sensory response or to deficits
in regulating emotional reactions to stimuli has important implications for intervention.
Objective To determine differences in brain responses, habituation, and connectivity during�…