Development of white matter circuitry in infants with fragile X syndrome
Importance Fragile X syndrome (FXS) is a genetic neurodevelopmental disorder and the
most common inherited cause of intellectual disability in males. However, there are no
published data on brain development in children with FXS during infancy. Objective To
characterize the development of white matter at ages 6, 12, and 24 months in infants with
FXS compared with that of typically developing controls. Design, Setting, and Participants
Longitudinal behavioral and brain imaging data were collected at 1 or more time points from�…
most common inherited cause of intellectual disability in males. However, there are no
published data on brain development in children with FXS during infancy. Objective To
characterize the development of white matter at ages 6, 12, and 24 months in infants with
FXS compared with that of typically developing controls. Design, Setting, and Participants
Longitudinal behavioral and brain imaging data were collected at 1 or more time points from�…