Highlights•The gender difference in depression through the life span.•An emphasis on the
emergence of the gender difference in adolescence.•Cognitive vulnerabilities and stressors
as predictors of the gender difference.•The role of stress generation.•Research is needed to
test how well existing models explain the epidemiological data.This paper briefly reviews
several recent lines of psychosocial research on the gender difference in depression. By the
middle of adolescence and continuing at least until age 55, females are about twice as likely�…