Longitudinal study of amygdala volume and joint attention in 2-to 4-year-old children with autism

MW Mosconi, H Cody-Hazlett, MD Poe…�- Archives of general�…, 2009 - jamanetwork.com
Context Cerebral cortical volume enlargement has been reported in 2-to 4-year-olds with
autism. Little is known about the volume of subregions during this period of development.
The amygdala is hypothesized to be abnormal in volume and related to core clinical features
in autism. Objectives To examine amygdala volume at 2 years with follow-up at 4 years of
age in children with autism and to explore the relationship between amygdala volume and
selected behavioral features of autism. Design Longitudinal magnetic resonance imaging�…