The corticotropin-releasing hormone test in patients with posttraumatic stress disorder
MA Smith, J Davidson, JC Ritchie, H Kudler, S Lipper…�- Biological�…, 1989 - Elsevier
To evaluate the hypothalamic—pituitary-adrenal (HPA) axis in patients with posttraumatic
stress disorder (PTSD), we measured adrenocorticotropin hormone (ACTH) and cortisol
responses following administration of corticotropin-releasing hormone (CRH) in 8 combat
veterans with chronic PTSD. The PTSD patients had a significantly lower ACTH response to
CRH compared to a control group of normal volunteers. Blunted ACTH responses occurred
in patients with PTSD alone, as well as those PTSD patients who also had major�…
stress disorder (PTSD), we measured adrenocorticotropin hormone (ACTH) and cortisol
responses following administration of corticotropin-releasing hormone (CRH) in 8 combat
veterans with chronic PTSD. The PTSD patients had a significantly lower ACTH response to
CRH compared to a control group of normal volunteers. Blunted ACTH responses occurred
in patients with PTSD alone, as well as those PTSD patients who also had major�…