Pd-catalyzed atom-economic couplings of triarylbismuth reagents with 2-bromo-and 2, 6-dibromochromones and synthesis of medicinally important fisetin
Pd-catalyzed mono-and bis-arylation of chromones was demonstrated using triarylbismuths
as threefold aryl transfer atom-economic reagents. This unprecedented study involving
functionalized chromones afforded regio-selective mono-arylations leading to functionalized
2-arylchromones in good to high yields. Bis-arylation of 2, 6-dibromochromones in one-pot
operation furnished 2, 6-diarylchromones in moderate to good yields. The present
methodology was applied in the synthesis of naturally occurring and medicinally important�…
as threefold aryl transfer atom-economic reagents. This unprecedented study involving
functionalized chromones afforded regio-selective mono-arylations leading to functionalized
2-arylchromones in good to high yields. Bis-arylation of 2, 6-dibromochromones in one-pot
operation furnished 2, 6-diarylchromones in moderate to good yields. The present
methodology was applied in the synthesis of naturally occurring and medicinally important�…