In the present study, we investigated whether mild-intensity physical exercise represents a
successful strategy to enhance spatial learning and memory and hippocampal plasticity in
aging rats, as previously described for long-term exposure to running wheel or treadmill
exercise. Aging Wistar rats were submitted to short bouts (4–6min) of exercise treadmill
during five consecutive weeks. This mild-intensity exercise program increased muscle
oxygen consumption by soleus and heart in aging rats and reversed age-related long-term�…