Trajectories of autism severity in children using standardized ADOS scores
OBJECTIVES: To plot longitudinal trajectories of autism spectrum disorder (ASD) severity
from early childhood to early adolescence. In line with reported trajectories in toddlers, we
hypothesize that a substantial minority of children will show marked changes in ASD severity
over time, with “Improvers” demonstrating the highest mean baseline and rate of growth in
verbal IQ (VIQ). METHODS: Patients included 345 clinic referrals and research participants
with best-estimate clinical diagnoses of ASD at 1 or more time points, and repeated Autism�…
from early childhood to early adolescence. In line with reported trajectories in toddlers, we
hypothesize that a substantial minority of children will show marked changes in ASD severity
over time, with “Improvers” demonstrating the highest mean baseline and rate of growth in
verbal IQ (VIQ). METHODS: Patients included 345 clinic referrals and research participants
with best-estimate clinical diagnoses of ASD at 1 or more time points, and repeated Autism�…