Fatty acid synthase, Her2/neu, and E2F1 as prognostic markers of progression in non-muscle invasive bladder cancer

AE Abdelrahman, HE Rashed, E Elkady…�- Annals of diagnostic�…, 2019 - Elsevier
Non-muscle-invasive bladder cancer (NMIBC) is a heterogeneous disease which has an
unpredictable risk of progression to muscle-invasive bladder cancer (MIBC). The selection of
patients who may benefit from early radical intervention is a challenge. To define the useful
prognostic markers for progression, we analyzed the immunohistochemical expression of
fatty acid synthase (FASN), Her2/neu, and E2F1 in 60 cases of NMIBC who underwent
TURBT and adjuvant intravesical bacillus-Calmette-Gu�rin (BCG). Their predicting role for�…