Sample results86 results in the last year.
Autism spectrum disorder: neurodevelopmental risk factors, biological mechanism, and precision therapy
Autism spectrum disorder (ASD) is a heterogeneous, behaviorally defined
neurodevelopmental disorder. Over the past two decades, the prevalence of autism
spectrum disorders has progressively increased, however, no clear diagnostic�…
neurodevelopmental disorder. Over the past two decades, the prevalence of autism
spectrum disorders has progressively increased, however, no clear diagnostic�…
mTOR signaling disruption and its association with the development of autism spectrum disorder
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder
characterized by impairments in social interaction and communication along with
repetitive stereotypic behaviors. Currently, there are no specific biomarkers for�…
characterized by impairments in social interaction and communication along with
repetitive stereotypic behaviors. Currently, there are no specific biomarkers for�…
Inflammation and the potential implication of macrophage-microglia polarization in human ASD: an overview
Autism spectrum disorder (ASD) is a heterogeneous collection of
neurodevelopmental disorders, difficult to diagnose and currently lacking treatment
options. The possibility of finding reliable biomarkers useful for early identification�…
neurodevelopmental disorders, difficult to diagnose and currently lacking treatment
options. The possibility of finding reliable biomarkers useful for early identification�…
Inflammatory mediators drive neuroinflammation in autism spectrum disorder and cerebral palsy
Inflammation conditions are associated with autism spectrum disorder (ASD) and
cerebral palsy (CP), primarily observed in the peripheral immune system. However,
the extent of neuro-inflammation and neuro-immune dysregulation remains poorly�…
cerebral palsy (CP), primarily observed in the peripheral immune system. However,
the extent of neuro-inflammation and neuro-immune dysregulation remains poorly�…
Autistic spectrum disorder (ASD)–Gene, molecular and pathway signatures linking systemic inflammation, mitochondrial dysfunction, transsynaptic signalling, and�…
Background Despite advances in autism spectrum disorder (ASD) research and the
vast genomic, transcriptomic, and proteomic data available, there are still
controversies regarding the pathways and molecular signatures underlying the�…
vast genomic, transcriptomic, and proteomic data available, there are still
controversies regarding the pathways and molecular signatures underlying the�…
Association between heavy metals exposure (cadmium, lead, arsenic, mercury) and child autistic disorder: A systematic review and meta-analysis
Background Studies have found that toxic heavy metals exposure could induce the
generation of reactive oxygen species (ROS), and is of epigenetic effect, which might
be associated with the occurrence of Autistic Disorder (ASD). This systematic review�…
generation of reactive oxygen species (ROS), and is of epigenetic effect, which might
be associated with the occurrence of Autistic Disorder (ASD). This systematic review�…
Modulation of PI3K/Akt/GSK3β signaling cascade through G protein-coupled receptor 55 (GPR55) activation: prenatal lysophosphatidylinositol attenuates valproic�…
Abstract Aims Dysregulation of PI3K/Akt/GSK3β signaling has been implicated in
various neurological disorders, including autism spectrum disorder (ASD). G protein-
coupled receptor 55 (GPR55) has recently emerged as a potential regulator of this�…
various neurological disorders, including autism spectrum disorder (ASD). G protein-
coupled receptor 55 (GPR55) has recently emerged as a potential regulator of this�…
Neurodevelopmental disorders and cancer networks share pathways, but differ in mechanisms, signaling strength, and outcome
Epidemiological studies suggest that individuals with neurodevelopmental disorders
(NDDs) are more prone to develop certain types of cancer. Notably, however, the
case statistics can be impacted by late discovery of cancer in individuals afflicted with�…
(NDDs) are more prone to develop certain types of cancer. Notably, however, the
case statistics can be impacted by late discovery of cancer in individuals afflicted with�…
Intermittent Hypobaric Hypoxia Ameliorates Autistic-Like Phenotypes in Mice
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by
persistent deficits in social communication and stereotyped behaviors. Although
major advances in basic research on autism have been achieved in the past decade�…
persistent deficits in social communication and stereotyped behaviors. Although
major advances in basic research on autism have been achieved in the past decade�…
Dendritic spine and synapse pathology in chromatin modifier-associated autism spectrum disorders and intellectual disability
Formation of dendritic spine and synapse is an essential final step of brain wiring to
establish functional communication in the developing brain. Recent findings have
displayed altered dendritic spine and synapse morphogenesis, plasticity, and related�…
establish functional communication in the developing brain. Recent findings have
displayed altered dendritic spine and synapse morphogenesis, plasticity, and related�…