Recently, the increasing prevalence of diabetes mellitus has made it a major chronic illness
which poses a substantial threat to human health. The prevalence of osteoporosis among�…

Abstract Type 1 diabetes (T1D) is associated with an increased fracture risk, which is
present at young and old age. Reductions in bone mineral density do not explain the�…

ISPAD Clinical Practice Consensus Guidelines 2022: Other complications and associated
conditions in children and adolescents wit Page 1 ISPAD GUIDELINES ISPAD Clinical Practice�…

Rationale: Mechanisms underlying the compromised bone formation in type 1 diabetes
mellitus (T1DM), which causes bone fragility and frequent fractures, remain poorly�…

Bone marrow adipose tissue (BMAT) is a unique adipose depot originating from bone
marrow stromal stem cells (BMSCs) and regulates bone homeostasis and energy�…

Context Skeletal fragility is a significant complication of type 1 diabetes (T1D), with an
increased risk of fracture observed starting in childhood. Altered bone accrual and�…

The study of bone has for many years been focused on the study of its mineralized
component, and one of the main objects of study as radiology developed as a medical�…

This paper gives an overview of the impact of type 1 diabetes on bone health in children and
adolescents. Firstly, we analyse studies using dual X-ray absorptiometry to assess bone�…

Type 1 diabetes (T1D) is one of the most common chronic diseases in childhood, with a
progressively increasing incidence. T1D management requires lifelong insulin treatment�…

Deficits in bone mineral and weaker bone structure in children with type 1 diabetes (T1D)
may contribute to a lifelong risk of fracture. However, there is no meta-analysis comparing�…