Estrogen receptors (ER) include ER alpha, ER beta and new membrane receptor G protein-
coupled receptor 30 (GPR30). Estrogen receptors are key receptors to maintain ovarian�…

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of
reproductive age. Despite its incidence, the syndrome is poorly understood and remains�…

Polycystic Ovary Syndrome (PCOS) is a complex condition with mechanisms likely to involve
the interaction between genetics and lifestyle. Familial clustering of PCOS symptoms is well�…

Polycystic ovary syndrome (PCOS) is an endocrine-metabolic disease affecting about 20–
25% of women in reproductive age. Different mechanisms could contribute to the�…

Polycystic ovary syndrome (PCOS) is typically characterized by a polycystic ovarian
morphology, hyperandrogenism, ovulatory dysfunction, and infertility. Furthermore, PCOS�…

The treatment of polycystic ovary syndrome (PCOS) faces challenges as all known
treatments are merely symptomatic. The US Food and Drug Administration (FDA) has not�…

STUDY QUESTION Does 12 weeks of high-intensity interval training (HIIT) result in greater
improvements in cardio-metabolic and reproductive outcomes compared to standard�…

Indian rhesus macaque nonhuman primate models for polycystic ovary syndrome (PCOS)
implicate both female hyperandrogenism and developmental molecular origins as core�…

Nearly all human complex traits and diseases exhibit some degree of sex differences, with
epigenetics being one of the main contributing factors. Various tissues display sex�…

Polycystic ovary syndrome (PCOS) is often associated with aberrant DNA methylation.
Despite the advances in diagnostics and treatment of PCOS, the pathophysiological�…