Background A preponderance of periapical radiolucencies are of inflammatory etiology
(radicular cysts or periapical granulomas) secondary to pulpal disease. In some instances,
however, a suspected periapical inflammatory lesion is not a consequence of pulpal disease
but instead represents a lesion of noninflammatory origin. The differential diagnosis for such
lesions is broad, ranging from odontogenic cysts and tumors to metastatic disease. As the
biological behavior of such lesions is varied, the distinction between inflammatory�…