Background Major depression is the largest single cause of nonfatal disease burden in
Australia. Effective drug and psychological treatments exist, yet are underused. Objective To
quantify the burden of disease currently averted in people seeking care for major depression
and the amount of disease burden that could be averted in these people under optimal
episodic and maintenance treatment strategies. Design Modeling impact of current and
optimal treatment strategies based on secondary analysis of mental health survey data�…