Short chain fatty acids as the luminal trophic factor

T Sakata�- Canadian Journal of Animal Science, 1984 - cdnsciencepub.com
Canadian Journal of Animal Science, 1984cdnsciencepub.com
Trophic effect of short chain fatty acids (SCFA) was studied in ileostomized rats using a
metaphase arrest technique. SCFA (acetate 100, propionate 20, butyrate 60 (mM), 2
mL/day) injected into the terminal ileum for 14 days increased the cryptal cell production rate
of the small and large intestine by 52–99%. Key words: Fatty acid, rat, ileum, cell division,
trophic effect
Trophic effect of short chain fatty acids (SCFA) was studied in ileostomized rats using a metaphase arrest technique. SCFA (acetate 100, propionate 20, butyrate 60 (mM), 2 mL/day) injected into the terminal ileum for 14 days increased the cryptal cell production rate of the small and large intestine by 52–99%. Key words: Fatty acid, rat, ileum, cell division, trophic effect
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