Pre-eclampsia remains a leading cause of maternal and perinatal mortality and morbidity. It
is a pregnancy-specific disease characterised by de-novo development of concurrent
hypertension and proteinuria, sometimes progressing into a multiorgan cluster of varying
clinical features. Poor early placentation is especially associated with early onset disease.
Predisposing cardiovascular or metabolic risks for endothelial dysfunction, as part of an
exaggerated systemic inflammatory response, might dominate in the origins of late onset pre�…

Norval Strachan and Ken Forbes (Aug 28, p 665) 1 highlight the increasing epidemic of
human campylo bacteriosis in the UK. They describe how source attribution models have
identified poultry as the major vehicle for human infection. 2 Furthermore, they report how
interventions to reduce campylobacter in poultry overseas have led to concurrent reductions
in the incidence of human disease. We write to highlight the alarming trend of increasing
ciprofloxacin resistance among UK human campylobacter isolates, an observation omitted�…