OBJECTIVES. Respiratory syncytial virus is the single-most important cause of lower
respiratory tract infections in children. Preterm birth and congenital heart disease are known
risk factors for severe respiratory syncytial virus infections. Although Down syndrome is
associated with a high risk of respiratory tract infections, little is known about the incidence of
respiratory syncytial virus infections in this group. The aim of our study was to determine the
incidence of respiratory syncytial virus lower respiratory tract infection–associated�…