Dendritic signalling and homeostatic adaptation
MY Lily, Y Goda�- Current opinion in neurobiology, 2009 - Elsevier
MY Lily, Y Goda
Current opinion in neurobiology, 2009•ElsevierHomeostatic plasticity mechanisms are employed by neurons to alter membrane excitability
and synaptic strength to adapt to changes in network activity. Recent studies suggest that
homeostatic processes can occur not only on a global scale but also within specific neuronal
subcompartments, involving a wide range of molecules and signalling pathways. Here, we
review new findings into homeostatic adaptation within dendrites and discuss potential
signalling components and mechanisms that may mediate this local form of regulation.
and synaptic strength to adapt to changes in network activity. Recent studies suggest that
homeostatic processes can occur not only on a global scale but also within specific neuronal
subcompartments, involving a wide range of molecules and signalling pathways. Here, we
review new findings into homeostatic adaptation within dendrites and discuss potential
signalling components and mechanisms that may mediate this local form of regulation.
Homeostatic plasticity mechanisms are employed by neurons to alter membrane excitability and synaptic strength to adapt to changes in network activity. Recent studies suggest that homeostatic processes can occur not only on a global scale but also within specific neuronal subcompartments, involving a wide range of molecules and signalling pathways. Here, we review new findings into homeostatic adaptation within dendrites and discuss potential signalling components and mechanisms that may mediate this local form of regulation.
Elsevier
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