Initial laboratory results from MFC tests using swine waste indicated that improvements to power output could be achieved with a carbon-fabric pleats design when compared to a previous packed bed design. An 88-liter pilot scale demonstration system was developed based on these results that allowed for full system operation in an energy neutral configuration. Initial results from the startup phase, showed an 80% decrease in chemical oxygen demand (COD) with a 7-day treatment time (fed-batch mode). During continuous flow operation, an average of 93% COD removal was observed.