[HTML][HTML] Acute kidney injury in diabetes mellitus: epidemiology, diagnostic and therapeutic concepts
Acute kidney injury (AKI) and diabetes mellitus (DM) are public health problems that cause a
high socioeconomic burden worldwide. In recent years, the landscape of AKI etiology has�…
high socioeconomic burden worldwide. In recent years, the landscape of AKI etiology has�…
[HTML][HTML] Calponin 2 regulates ketogenesis to mitigate acute kidney injury
Abstract Calponin 2 (CNN2) is a prominent actin stabilizer. It regulates fatty acid oxidation
(FAO) by interacting with estrogen receptor 2 (ESR2) to determine kidney fibrosis. However�…
(FAO) by interacting with estrogen receptor 2 (ESR2) to determine kidney fibrosis. However�…
[HTML][HTML] Calponin 2 harnesses metabolic reprogramming to determine kidney fibrosis
Y Gui, Y Wang, Z Palanza, JL Wang, P Gupta, J Tao…�- Molecular�…, 2023 - Elsevier
Objective In the fibrotic kidneys, the extent of a formed deleterious microenvironment is
determined by cellular mechanical forces. This process requires metabolism for energy�…
determined by cellular mechanical forces. This process requires metabolism for energy�…
Fibroblast expression of transmembrane protein smoothened governs microenvironment characteristics after acute kidney injury
The smoothened (Smo) receptor facilitates hedgehog signaling between kidney fibroblasts
and tubules during acute kidney injury (AKI). Tubule-derived hedgehog is protective in AKI�…
and tubules during acute kidney injury (AKI). Tubule-derived hedgehog is protective in AKI�…
Acute Kidney Injury in the Elderly
Z Palanza - 2023 - digitalcommons.lib.uconn.edu
Acute kidney injury (AKI) is a significant clinical concern in the elderly, marked by
heightened incidence rates, increased morbidity and mortality, and impaired kidney repair�…
heightened incidence rates, increased morbidity and mortality, and impaired kidney repair�…
[PDF][PDF] Fibroblast-selective smoothened governs the prognosis of acute kidney injury
The smoothened (Smo) receptor facilitates hedgehog signaling between kidney broblasts
and tubules during acute kidney injury (AKI). Tubule-derived hedgehog is protective in AKI�…
and tubules during acute kidney injury (AKI). Tubule-derived hedgehog is protective in AKI�…