ATP acts as a humoral mediator to control cell function extracellularly. The receptors that
mediate the actions of ATP belong to two classes, the metabotropic P2Y receptors and the�…

Eosinophilia may be responsible for cardiac injuries of widely varying severity, from acute
myocarditis to endomyocardial fibrosis. In this review, we present both the molecular�…

Chronic pain is a highly prevalent debilitating condition for which treatment options remain
limited for many patients. Ionotropic ATP signalling through excitatory and calcium�…

A full-length clone coding for the rat alpha 7 nicotinic receptor subunit was isolated from an
adult brain cDNA library and expressed in Xenopus oocytes. A significant proportion of the�…

Ionotropic ATP receptors are widely expressed in mammalian CNS. Despite extensive
functional characterization of neuronal homomeric P2X receptors in heterologous�…

Body fluid homeostasis requires the release of arginine-vasopressin (AVP, an antidiuretic
hormone) from the neurohypophysis. This release is controlled by specific and highly�…

We report a novel model in which remote activation of peripheral nociceptive pathways in
transgenic mice is achieved optogenetically, without any external noxious stimulus or injury�…

Objective: To investigate and measure the functional significance of altered P2Y12
expression in the context of human microglia activation. Methods: We performed in vitro and�…

The absence of fragile X mental retardation protein results in the fragile X syndrome (FXS), a
common form of mental retardation associated with attention deficit, autistic behavior, and�…

PAP immunocytochemistry with an antiserum against serotonin (5‐HT)‐glutaraldehyde‐
protein conjugate (kindly donated by M. Geffard) was used to analyze the ultrastructural�…