The use of pigs in neuroscience research has increased in the past decade, which has seen
broader recognition of the potential of pigs as an animal for experimental modeling of�…

Liraglutide is a glucagon-like peptide-1 (GLP-1) analog marketed for the treatment of type 2
diabetes. Besides lowering blood glucose, liraglutide also reduces body weight. It is not fully�…

Aim: Previous studies with the novel once daily glucagon‐like peptide‐1 (GLP‐1) analogue
liraglutide and the GLP‐1 receptor agonist exenatide have revealed profound�…

Diffusion weighted imaging (DWI) and tractography allow the non-invasive study of
anatomical brain connectivity. However, a gold standard for validating tractography of�…

The first mathematically unbiased estimates of neocortical cell numbers are presented from
the developing pig brain, including a full description of tissue processing and optimal�…

Nonalcoholic fatty liver disease (NAFLD) represents a spectrum of conditions ranging from
simple steatosis (NAFL), over nonalcoholic steatohepatitis (NASH) with or without fibrosis, to�…

Diffusion tensor (DT) imaging and related multifiber reconstruction algorithms allow the
study of in vivo microstructure and, by means of tractography, structural connectivity�…

Recent studies indicate that glucagon-like peptide 1 (GLP-1) receptor agonists, currently
used in the management of type 2 diabetes, exhibit neurotrophic and neuroprotective effects�…

Aims/hypothesis Enteroendocrine K and L cells are pivotal in regulating appetite and
glucose homeostasis. Knowledge of their distribution in humans is sparse and it is unknown�…

Background and Aims Roux-en-Y gastric bypass (RYGB) leads to a rapid remission of type 2
diabetes mellitus (T2DM), but the underlying mode of action remains incompletely�…