Clinical practice guideline for Sj�gren's syndrome 2017
…, M Moriyama, H Takahashi, H Asashima…�- Modern�…, 2018 - academic.oup.com
Objectives: The objective of this study is to develop clinical practice guideline (CPG) for
Sj�gren's syndrome (SS) based on recently available clinical and therapeutic evidences�…
Sj�gren's syndrome (SS) based on recently available clinical and therapeutic evidences�…
[HTML][HTML] Immune dysregulation and autoreactivity correlate with disease severity in SARS-CoV-2-associated multisystem inflammatory syndrome in children
…, NN Brodsky, TS Sumida, M Comi, H Asashima…�- Immunity, 2021 - cell.com
Multisystem inflammatory syndrome in children (MIS-C) is a life-threatening post-infectious
complication occurring unpredictably weeks after mild or asymptomatic SARS-CoV-2�…
complication occurring unpredictably weeks after mild or asymptomatic SARS-CoV-2�…
[HTML][HTML] PD-1highCXCR5–CD4+ peripheral helper T cells promote CXCR3+ plasmablasts in human acute viral infection
T cell-B cell interaction is the key immune response to protect the host from severe viral
infection. However, how T cells support B cells to exert protective humoral immunity in�…
infection. However, how T cells support B cells to exert protective humoral immunity in�…
The role of M3 muscarinic acetylcholine receptor reactive T cells in Sj�gren's syndrome: a critical review
…, H Tsuboi, M Iizuka, T Hirota, H Asashima…�- Journal of�…, 2014 - Elsevier
CD4+ T cells constitute the majority of infiltrating cells in salivary glands and lachrymal
glands of patients with Sj�gren's syndrome (SS). The pathophysiology of SS involves T cell�…
glands of patients with Sj�gren's syndrome (SS). The pathophysiology of SS involves T cell�…
[HTML][HTML] High-plex protein and whole transcriptome co-mapping at cellular resolution with spatial CITE-seq
In this study, we extended co-indexing of transcriptomes and epitopes (CITE) to the spatial
dimension and demonstrated high-plex protein and whole transcriptome co-mapping. We�…
dimension and demonstrated high-plex protein and whole transcriptome co-mapping. We�…
[HTML][HTML] Impaired TIGIT expression on B cells drives circulating follicular helper T cell expansion in multiple sclerosis
H Asashima, PP Axisa, THG Pham…�- The Journal of�…, 2022 - Am Soc Clin Investig
B cell depletion in patients with relapsing-remitting multiple sclerosis (RRMS) markedly
prevents new MRI-detected lesions and disease activity, suggesting the hypothesis that�…
prevents new MRI-detected lesions and disease activity, suggesting the hypothesis that�…
[HTML][HTML] Single-cell multi-omics reveals dyssynchrony of the innate and adaptive immune system in progressive COVID-19
…, AY Zhao, V Gasque, JC Schupp, H Asashima…�- Nature�…, 2022 - nature.com
Dysregulated immune responses against the SARS-CoV-2 virus are instrumental in severe
COVID-19. However, the immune signatures associated with immunopathology are poorly�…
COVID-19. However, the immune signatures associated with immunopathology are poorly�…
Anti-M3 muscarinic acetylcholine receptor antibodies in patients with Sj�gren's syndrome
T Sumida, H Tsuboi, M Iizuka, H Asashima…�- Modern�…, 2013 - academic.oup.com
Sj�gren's syndrome (SS) is an autoimmune disease that affects exocrine glands including
salivary and lacrimal glands. Recently, autoantibodies against muscarinic acetylcholine�…
salivary and lacrimal glands. Recently, autoantibodies against muscarinic acetylcholine�…
[HTML][HTML] Prior cycles of anti-CD20 antibodies affect antibody responses after repeated SARS-CoV-2 mRNA vaccination
BACKGROUND While B cell depletion is associated with attenuated antibody responses to
SARS-CoV-2 mRNA vaccination, responses vary among individuals. Thus, elucidating the�…
SARS-CoV-2 mRNA vaccination, responses vary among individuals. Thus, elucidating the�…
[HTML][HTML] Multi-omic longitudinal study reveals immune correlates of clinical course among hospitalized COVID-19 patients
…, ML Anderson, EJ Anderson, A Arnett, H Asashima…�- Cell Reports�…, 2023 - cell.com
The IMPACC cohort, composed of> 1,000 hospitalized COVID-19 participants, contains five
illness trajectory groups (TGs) during acute infection (first 28 days), ranging from milder (TG1�…
illness trajectory groups (TGs) during acute infection (first 28 days), ranging from milder (TG1�…