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Cedric Feschotte

Professor, Department of Molecular Biology and Genetics, Cornell University
Verified email at cornell.edu
Cited by 23427

DNA transposons and the evolution of eukaryotic genomes

C Feschotte, EJ Pritham�- Annu. Rev. Genet., 2007 - annualreviews.org
Transposable elements are mobile genetic units that exhibit broad diversity in their structure
and transposition mechanisms. Transposable elements occupy a large fraction of many�…

Endogenous viruses: insights into viral evolution and impact on host biology

C Feschotte, C Gilbert�- Nature Reviews Genetics, 2012 - nature.com
Recent studies have uncovered myriad viral sequences that are integrated
or'endogenized'in the genomes of various eukaryotes. Surprisingly, it appears that not just�…

Regulatory activities of transposable elements: from conflicts to benefits

EB Chuong, NC Elde, C Feschotte�- Nature Reviews Genetics, 2017 - nature.com
Transposable elements (TEs) are a prolific source of tightly regulated, biochemically active
non-coding elements, such as transcription factor-binding sites and non-coding RNAs. Many�…

RepeatModeler2 for automated genomic discovery of transposable element families

JM Flynn, R Hubley, C Goubert…�- Proceedings of the�…, 2020 - National Acad Sciences
The accelerating pace of genome sequencing throughout the tree of life is driving the need
for improved unsupervised annotation of genome components such as transposable�…

[HTML][HTML] Transposable elements are major contributors to the origin, diversification, and regulation of vertebrate long noncoding RNAs

A Kapusta, Z Kronenberg, VJ Lynch, X Zhuo…�- PLoS�…, 2013 - journals.plos.org
Advances in vertebrate genomics have uncovered thousands of loci encoding long
noncoding RNAs (lncRNAs). While progress has been made in elucidating the regulatory�…

Regulatory evolution of innate immunity through co-option of endogenous retroviruses

EB Chuong, NC Elde, C Feschotte�- Science, 2016 - science.org
Endogenous retroviruses (ERVs) are abundant in mammalian genomes and contain
sequences modulating transcription. The impact of ERV propagation on the evolution of�…

The evolutionary history of human DNA transposons: evidence for intense activity in the primate lineage

JK Pace, C Feschotte�- Genome research, 2007 - genome.cshlp.org
Class 2, or DNA transposons, make up∼ 3% of the human genome, yet the evolutionary
history of these elements has been largely overlooked and remains poorly understood. Here�…

Transposable elements and the evolution of regulatory networks

C Feschotte�- Nature Reviews Genetics, 2008 - nature.com
The control and coordination of eukaryotic gene expression rely on transcriptional and post-
transcriptional regulatory networks. Although progress has been made in mapping the�…

Plant transposable elements: where genetics meets genomics

C Feschotte, N Jiang, SR Wessler�- Nature Reviews Genetics, 2002 - nature.com
Transposable elements are the single largest component of the genetic material of most
eukaryotes. The recent availability of large quantities of genomic sequence has led to a shift�…

[HTML][HTML] Ten things you should know about transposable elements

G Bourque, KH Burns, M Gehring, V Gorbunova…�- Genome biology, 2018 - Springer
Transposable elements (TEs) are major components of eukaryotic genomes. However, the
extent of their impact on genome evolution, function, and disease remain a matter of intense�…