Previous reports demonstrate that metformin, an anti-diabetic drug, can decrease the risk of
cancer and inhibit cancer cell growth. However, its mechanism in cancer cells is still�…

The ubiquitin proteasome system (UPS) regulates many cellular functions by degrading key
proteins. Notably, the role of UPS in regulating mitochondrial metabolic functions is unclear�…

Cyberbullying is associated with negative mental health outcomes including adolescent
suicidal ideation. This requires effective and accessible preventive efforts. Healthy lifestyles�…

Fucosidosis is a rare, autosomal recessive, lysosomal storage disorder caused by a severe
deficiency of alpha-L-fucosidase in all tissues. We have conducted a review of fucosidosis�…

Objective This study examined associations of minority stressors (ie, victimization,
internalized homonegativity, and stigma consciousness), and coping styles (ie, active�…

Glioblastoma represents the highest grade of brain tumors. Despite maximal resection
surgery associated with radiotherapy and concomitant followed by adjuvant chemotherapy�…

Some cases of maternally inherited isolated deafness are caused by mtDNA mutations,
frequently following an exposure to aminoglycosides. Two mitochondrial genes have been�…

Sexual and gender minority (SGM) young adults are at higher risk for suicidal ideation and
attempts than heterosexual, cisgender young adults. Research concerning differences by�…

The basic understanding of the biological effects of eukaryotic translation initiation factors
(EIFs) remains incomplete, notably for their roles independent of protein translation. Different�…

Sexual minority emerging adults are more likely to engage in suicidal ideation than their
heterosexual counterparts. Experiences of homophobic violence are associated with�…