The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2;
previously provisionally named 2019 novel coronavirus or 2019-nCoV) disease (COVID-19)�…

Since the emergence of coronavirus disease 2019 (COVID-19)(formerly known as the 2019
novel coronavirus [2019-nCoV]) in Wuhan, China in December 2019, which is caused by�…

Co-infection has been reported in patients with severe acute respiratory syndrome (SARS)
and Middle East respiratory syndrome, but there is limited knowledge on co-infection among�…

Background and Methods In preliminary trials, lamivudine, an oral nucleoside analogue, has
shown promise for the treatment of chronic hepatitis B. We conducted a one-year, double�…

Background Entecavir is a potent and selective antiviral agent that has demonstrated
efficacy in phase 2 studies in patients with hepatitis B e antigen (HBeAg)–negative chronic�…

Background Reducing hepatitis B virus (HBV) replication to minimal levels is emerging as a
key therapeutic goal for chronic hepatitis B. Methods In this double-blind, phase 3 trial, 1370�…

YMDD variants of hepatitis B virus (HBV) emerge in some patients with chronic hepatitis B
who receive lamivudine. YMDD variants were examined in 794 patients in 4 controlled�…

A study in Chinese patients with chronic hepatitis B showed that treatment with lamivudine
for 1 year significantly improves liver histology and enhances hepatitis B e antigen (HBeAg)�…

Individuals affected with developmental disorders of speech and language have substantial
difficulty acquiring expressive and/or receptive language in the absence of any profound�…

The Daya Bay Reactor Neutrino Experiment has measured a nonzero value for the neutrino
mixing angle θ 13 with a significance of 5.2 standard deviations. Antineutrinos from six 2.9�…