Liraglutide is a glucagon-like peptide-1 (GLP-1) analog marketed for the treatment of type 2
diabetes. Besides lowering blood glucose, liraglutide also reduces body weight. It is not fully�…

Cognitive deficits persist in patients who survive traumatic brain injury (TBI). Lateral fluid
percussion brain injury in the mouse, a model of human TBI, results in hippocampal�…

Fluid percussion (FP) brain injury causes spatial memory dysfunction in rats regardless of
injury location (midline vs. lateral). Standard histological analysis of the injured brains shows�…

Cortical spreading depression (CSD) is associated with release of arachidonic acid,
impaired neurovascular coupling, and reduced cerebral blood flow (CBF), caused by cortical�…

Traumatic brain injury is a leading cause of death and disability in the United States.
Pathological examinations of humans and animal models after brain injury demonstrate�…

Conditioned fear associates a contextual environment and cue stimulus to a foot shock in a
single training trial, where fear expressed to the trained context or cue indicates cognitive�…

We present a novel method for nanoscale reconstruction of complex refractive index by
using scattering-type Scanning Near-field Optical Microscopy (s-SNOM). Our method relies�…

Traumatic brain injury (TBI) damages the hippocampus both in experimental animal models
and in humans. In particular, the mechanical injury in combination with the genetic�…

Evoked neural activity correlates strongly with rises in cerebral metabolic rate of oxygen
(CMRO2) and cerebral blood flow (CBF). Activity-dependent rises in CMRO2 fluctuate with�…

The quantification of ultrastructure has been permanently improved by the application of
new stereological principles. Both precision and efficiency have been enhanced. Here we�…