[HTML][HTML] Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain
Despite increasing evidence of oxidative stress in the pathophysiology of autism, most
studies have not evaluated biomarkers within specific brain regions, and the functional�…
studies have not evaluated biomarkers within specific brain regions, and the functional�…
Brain region-specific glutathione redox imbalance in autism
A Chauhan, T Audhya, V Chauhan�- Neurochemical research, 2012 - Springer
Autism is a heterogeneous, behaviorally defined neurodevelopmental disorder. Recently,
we reported a brain region–specific increase in lipid peroxidation, and deficits in�…
we reported a brain region–specific increase in lipid peroxidation, and deficits in�…
Impaired synthesis and antioxidant defense of glutathione in the cerebellum of autistic subjects: alterations in the activities and protein expression of glutathione�…
F Gu, V Chauhan, A Chauhan�- Free Radical Biology and Medicine, 2013 - Elsevier
Autism is a neurodevelopmental disorder associated with social deficits and behavioral
abnormalities. Recent evidence in autism suggests a deficit in glutathione (GSH), a major�…
abnormalities. Recent evidence in autism suggests a deficit in glutathione (GSH), a major�…
[HTML][HTML] Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived from children with autism
SJ James, S Rose, S Melnyk, S Jernigan…�- The FASEB�…, 2009 - ncbi.nlm.nih.gov
Research into the metabolic phenotype of autism has been relatively unexplored despite the
fact that metabolic abnormalities have been implicated in the pathophysiology of several�…
fact that metabolic abnormalities have been implicated in the pathophysiology of several�…
Oxidative stress in autism: elevated cerebellar 3-nitrotyrosine levels
EM Sajdel-Sulkowska, B Lipinski, H Windom…�- Am J Biochem�…, 2008 - hero.epa.gov
It has been suggested that oxidative stress and/or mercury compounds play an important
role in the pathophysiology of autism. This study compared for the first time the cerebellar�…
role in the pathophysiology of autism. This study compared for the first time the cerebellar�…
Glutathione-related factors and oxidative stress in autism, a review
A Ghanizadeh, S Akhondzadeh…�- Current medicinal�…, 2012 - ingentaconnect.com
Autism spectrum disorders are complex neuro-developmental disorders whose
neurobiology is proposed to be associated with oxidative stress which is induced by reactive�…
neurobiology is proposed to be associated with oxidative stress which is induced by reactive�…
Role of oxidative stress and antioxidants in autism
T Manivasagam, S Arunadevi, MM Essa…�- …�food intervention and�…, 2020 - Springer
Autism spectrum disorder (ASD) is a heterogeneous group of neurodevelopmental disorders
with poorly understood etiology that are defined exclusively on the basis of behavioral�…
with poorly understood etiology that are defined exclusively on the basis of behavioral�…
The role of glutathione redox imbalance in autism spectrum disorder: a review
G Bj�rklund, AA Tinkov, B Hosnedlov�, R Kizek…�- Free Radical Biology�…, 2020 - Elsevier
The role of glutathione in autism spectrum disorder (ASD) is emerging as a major topic, due
to its role in the maintenance of the intracellular redox balance. Several studies have�…
to its role in the maintenance of the intracellular redox balance. Several studies have�…
Oxidative stress in autism spectrum disorder
G Bj�rklund, NA Meguid, MA El-Bana, AA Tinkov…�- Molecular�…, 2020 - Springer
Abstract According to the United States Centers for Disease Control and Prevention (CDC),
as of July 11, 2016, the reported average incidence of children diagnosed with an autism�…
as of July 11, 2016, the reported average incidence of children diagnosed with an autism�…
Oxidative stress-related biomarkers in autism: systematic review and meta-analyses
Autism spectrum disorders (ASDs) are rarely diagnosed in children younger than 2 years,
because diagnosis is based entirely on behavioral tests. Oxidative damage may play a�…
because diagnosis is based entirely on behavioral tests. Oxidative damage may play a�…