Immune mediators in the brain and peripheral tissues in autism spectrum disorder

ML Estes, AK McAllister�- Nature Reviews Neuroscience, 2015 - nature.com
Increasing evidence points to a central role for immune dysregulation in autism spectrum
disorder (ASD). Several ASD risk genes encode components of the immune system and�…

Immune dysregulation in autism spectrum disorder

EY Hsiao�- International review of neurobiology, 2013 - Elsevier
Autism spectrum disorder (ASD) is a highly heterogeneous disorder diagnosed based on
the presence and severity of core abnormalities in social communication and repetitive�…

[HTML][HTML] The role of the immune system in autism spectrum disorder

A Meltzer, J Van de Water�- Neuropsychopharmacology, 2017 - nature.com
Autism is a neurodevelopmental disorder characterized by deficits in communication and
social skills as well as repetitive and stereotypical behaviors. While much effort has focused�…

Peripheral and central inflammation in autism spectrum disorders

AM Depino�- Molecular and Cellular Neuroscience, 2013 - Elsevier
Recent reports have given a central role to environmental factors in the etiology of autism
spectrum disorders (ASD). However, most proposed perinatal factors seem to converge into�…

Cytokine dysregulation in autism spectrum disorders (ASD): possible role of the environment

PE Goines, P Ashwood�- Neurotoxicology and teratology, 2013 - Elsevier
Autism spectrum disorders (ASD) are neurodevelopmental diseases that affect an alarming
number of individuals. The etiological basis of ASD is unclear, and evidence suggests it�…

[HTML][HTML] Immune abnormalities in autism spectrum disorder—could they hold promise for causative treatment?

D Gładysz, A Krzywdzińska, KK Hozyasz�- Molecular neurobiology, 2018 - Springer
Autism spectrum disorders (ASD) are characterized by impairments in language and
communication development, social behavior, and the occurrence of stereotypic patterns of�…

The role of immune dysfunction in the pathophysiology of autism

C Onore, M Careaga, P Ashwood�- Brain, behavior, and immunity, 2012 - Elsevier
Autism spectrum disorders (ASD) are a complex group of neurodevelopmental disorders
encompassing impairments in communication, social interactions and restricted�…

Toward an immune-mediated subtype of autism spectrum disorder

CJ McDougle, SM Landino, A Vahabzadeh, J O'Rourke…�- Brain research, 2015 - Elsevier
A role for immunological involvement in autism spectrum disorder (ASD) has long been
hypothesized. This review includes four sections describing (1) evidence for a relationship�…

[HTML][HTML] Immune dysfunction and autoimmunity as pathological mechanisms in autism spectrum disorders

HK Hughes, E Mills Ko, D Rose…�- Frontiers in cellular�…, 2018 - frontiersin.org
Autism spectrum disorders (ASD) are a group of heterogeneous neurological disorders that
are highly variable and are clinically characterized by deficits in social interactions�…

[HTML][HTML] The impact of neuroimmune alterations in autism spectrum disorder

C Gottfried, V Bambini-Junior, F Francis…�- Frontiers in�…, 2015 - frontiersin.org
Autism spectrum disorder (ASD) involves a complex interplay of both genetic and
environmental risk factors, with immune alterations and synaptic connection deficiency in�…