Drug, alcohol and tobacco use disorders are a global burden affecting millions of people.
Despite decades of research, treatment options are sparse or missing, and relapse rates are�…

Although the multifaceted mechanisms underlying alcohol use disorder (AUD) have been
partially defined, the neurobiological complexity of this disorder is yet to be unraveled. One�…

Abstract Glucagon-like peptide 1 (GLP-1) and its receptor GLP-1R are a key component of
the satiety signaling system, and long-acting GLP-1 analogs have been approved for the�…

Alcohol use disorder (AUD) is a chronic relapsing condition characterized by compulsive
alcohol-seeking behaviors, with serious detrimental health consequences. Despite high�…

GLP-1 receptor agonists are promising but unproven treatments for alcohol and substance use
disorders | Nature Medicine Skip to main content Thank you for visiting nature.com. You are�…

The hormone glucagon-like peptide-1 (GLP-1) regulates appetite and food intake. GLP-1
receptor (GLP-1R) activation also attenuates the reinforcing properties of alcohol in rodents�…

Recent data implicate glucagon-like peptide-1 (GLP-1), a potent anorexigenic peptide
released in response to nutrient intake, as a regulator for the reinforcing properties of food�…

The role of glucagon-like peptide 1 (GLP-1) in insulin-dependent signaling is well-known;
GLP-1 enhances glucose-dependent insulin secretion and lowers blood glucose in�…

Introduced less than two decades ago, glucagon‐like peptide‐1 receptor agonists rapidly
reshaped the field of Type 2 diabetes mellitus (T2DM) care by providing glycaemic control in�…

The incretin hormone glucagon‐like peptide‐1 (GLP‐1) is inactivated by the enzyme
dipeptidyl peptidase‐4 even before it leaves the gut, but it seems to act predominantly via�…