[HTML][HTML] Autism spectrum disorder: neurodevelopmental risk factors, biological mechanism, and precision therapy

L Wang, B Wang, C Wu, J Wang, M Sun�- International journal of�…, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a heterogeneous, behaviorally defined
neurodevelopmental disorder. Over the past two decades, the prevalence of autism�…

Autism spectrum disorder: signaling pathways and prospective therapeutic targets

J Baranova, G Dragunas, MCS Botellho…�- Cellular and molecular�…, 2021 - Springer
Abstract The Autism Spectrum Disorder (ASD) consists of a prevalent and heterogeneous
group of neurodevelopmental diseases representing a severe burden to affected individuals�…

[HTML][HTML] Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications

CC Jiang, LS Lin, S Long, XY Ke, K Fukunaga…�- Signal transduction and�…, 2022 - nature.com
Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known�…

Future directions for research in autism spectrum disorders

CR Damiano, CA Mazefsky, SW White…�- Journal of Clinical Child�…, 2014 - Taylor & Francis
This article suggests future directions for research aimed at improving our understanding of
the etiology and pathophysiology of autism spectrum disorder (ASD) as well as�…

[HTML][HTML] Genetic causes and modifiers of autism spectrum disorder

L Rylaarsdam, A Guemez-Gamboa�- Frontiers in cellular�…, 2019 - frontiersin.org
Autism Spectrum Disorder (ASD) is one of the most prevalent neurodevelopmental
disorders, affecting an estimated 1 in 59 children. ASD is highly genetically heterogeneous�…

Advances in autism

DH Geschwind�- Annual review of medicine, 2009 - annualreviews.org
Autism is a common childhood neurodevelopmental disorder with strong genetic liability. It is
not a unitary entity but a clinical syndrome, with variable deficits in social behavior and�…

Overview of the recent advances in pathophysiology and treatment for autism

H Famitafreshi, M Karimian�- CNS & Neurological Disorders�…, 2018 - ingentaconnect.com
Background & Objective: Autism is a developmental disorder that manifests itself in early
childhood. Autism is characterized by inability to acquire social skills, repetitive behaviors�…

[HTML][HTML] Impaired neurodevelopmental pathways in autism spectrum disorder: a review of signaling mechanisms and crosstalk

S Kumar, K Reynolds, Y Ji, R Gu, S Rai…�- Journal of�…, 2019 - Springer
Background The development of an autistic brain is a highly complex process as evident
from the involvement of various genetic and non-genetic factors in the etiology of the autism�…

Genetics and epigenetics of autism: A Review

MMY Waye, HY Cheng�- Psychiatry and clinical neurosciences, 2018 - Wiley Online Library
Autism is a developmental disorder that starts before age 3 years, and children with autism
have impairment in both social interaction and communication, and have restricted�…

Phenotyping, etiological factors, and biomarkers: toward precision medicine in autism spectrum disorders

DQ Beversdorf�- Journal of Developmental & Behavioral�…, 2016 - journals.lww.com
Despite the progress made in understanding the biology of autism spectrum disorder (ASD),
effective biological interventions for the core symptoms remain elusive. Because of the�…