Cytokine dysregulation in autism spectrum disorders (ASD): possible role of the environment

PE Goines, P Ashwood�- Neurotoxicology and teratology, 2013 - Elsevier
Autism spectrum disorders (ASD) are neurodevelopmental diseases that affect an alarming
number of individuals. The etiological basis of ASD is unclear, and evidence suggests it�…

Immune mediators in the brain and peripheral tissues in autism spectrum disorder

ML Estes, AK McAllister�- Nature Reviews Neuroscience, 2015 - nature.com
Increasing evidence points to a central role for immune dysregulation in autism spectrum
disorder (ASD). Several ASD risk genes encode components of the immune system and�…

Peripheral and central inflammation in autism spectrum disorders

AM Depino�- Molecular and Cellular Neuroscience, 2013 - Elsevier
Recent reports have given a central role to environmental factors in the etiology of autism
spectrum disorders (ASD). However, most proposed perinatal factors seem to converge into�…

[HTML][HTML] The immune system, cytokines, and biomarkers in autism spectrum disorder

A Masi, N Glozier, R Dale, AJ Guastella�- Neuroscience bulletin, 2017 - Springer
Abstract Autism Spectrum Disorder (ASD) is a pervasive neurodevelopmental condition
characterized by variable impairments in communication and social interaction as well as�…

Immune dysregulation in autism spectrum disorder

EY Hsiao�- International review of neurobiology, 2013 - Elsevier
Autism spectrum disorder (ASD) is a highly heterogeneous disorder diagnosed based on
the presence and severity of core abnormalities in social communication and repetitive�…

[HTML][HTML] Immune abnormalities in autism spectrum disorder—could they hold promise for causative treatment?

D Gładysz, A Krzywdzińska, KK Hozyasz�- Molecular neurobiology, 2018 - Springer
Autism spectrum disorders (ASD) are characterized by impairments in language and
communication development, social behavior, and the occurrence of stereotypic patterns of�…

Immune dysfunction in autism: a pathway to treatment

M Careaga, J Van de Water, P Ashwood�- Neurotherapeutics, 2010 - Elsevier
Autism is a complex and clinically heterogeneous disorder with a spectrum of symptoms.
Clinicians, schools, and service agencies worldwide have reported a dramatic increase in�…

[HTML][HTML] Immune dysfunction and autoimmunity as pathological mechanisms in autism spectrum disorders

HK Hughes, E Mills Ko, D Rose…�- Frontiers in cellular�…, 2018 - frontiersin.org
Autism spectrum disorders (ASD) are a group of heterogeneous neurological disorders that
are highly variable and are clinically characterized by deficits in social interactions�…

Risk factors in autism: Thinking outside the brain

L Matelski, J Van de Water�- Journal of autoimmunity, 2016 - Elsevier
Autism spectrum disorders (ASD) are complex neurodevelopmental conditions that have
been rising markedly in prevalence for the past 30 years, now thought to affect 1 in 68 in the�…

[HTML][HTML] The role of the immune system in autism spectrum disorder

A Meltzer, J Van de Water�- Neuropsychopharmacology, 2017 - nature.com
Autism is a neurodevelopmental disorder characterized by deficits in communication and
social skills as well as repetitive and stereotypical behaviors. While much effort has focused�…