Altered synaptic structure and function is a major hallmark of fragile X syndrome (FXS),
autism spectrum disorders (ASDs), and other intellectual disabilities (IDs), which are�…

Fragile X syndrome (FXS) is the most common form of monogenic hereditary cognitive
impairment. FXS patient exhibit a high comorbidity rate with autism spectrum disorders�…

Fragile X syndrome (FXS) is the most common inherited form of mental retardation and a
leading genetic cause of autism. There is increasing evidence in both FXS and other forms�…

Fragile X syndrome (FXS), a heritable intellectual and autism spectrum disorder (ASD),
results from the loss of Fragile X mental retardation protein (FMRP). This�…

Fragile X syndrome (FXS) mental retardation is caused by loss-of-function mutations in an
RNA-binding protein, fragile X mental retardation protein (FMRP). Previous studies in�…

Fragile X syndrome, as well as other forms of mental retardation and autism, is associated
with altered dendritic spine number and structure. Fragile X syndrome is caused by loss-of�…

Fragile X syndrome (FXS) is the most common inherited form of intellectual disability and the
leading genetic cause of autism. It is associated with the lack of fragile X mental retardation�…

Fragile X is the most common known inherited cause of intellectual disability and autism,
and it typically results from transcriptional silencing of FMR1 and loss of the encoded�…

Proper brain function requires stringent balance of excitatory and inhibitory synapse
formation during neural circuit assembly. Mutation of genes that normally sculpt and�…

Fragile X syndrome (FraX), caused by the loss-of-function of one gene (FMR1), is the most
common inherited form of both mental retardation and autism spectrum disorders. The FMR1�…