Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized
by impairments in social interaction and communication along with repetitive stereotypic�…

Whereas autism spectrum disorder (ASD) exhibits striking heterogeneity in genetics and
clinical presentation, dysfunction of mechanistic target of rapamycin complex 1 (mTORC1)�…

Abstract PI3K-AKT/mTOR signaling pathway represents an essential signaling mechanism
for mammalian enzyme-related receptors in transducing signals or biological processes�…

Autism spectrum disorder (ASD) is a complex neurodevelopmental monogenic disorder with
a strong genetic influence. Idiopathic autism could be defined as a type of autism that does�…

Autism spectrum disorders (ASDs) are a group of clinically and genetically heterogeneous
neurodevelopmental disorders characterized by impaired social interactions, repetitive�…

The molecular signature underlying autism spectrum disorder remains largely unknown.
This study identifies differential expression of mTOR and MAPK pathways in patients�…

The mechanistic target of rapamycin (mTOR) is an important signaling hub that integrates
environmental information regarding energy availability and stimulates anabolic molecular�…

Mammalian target of rapamycin (mTOR) is a key regulator in various cellular processes,
including cell growth, gene expression, and synaptic functions. Autism spectrum disorder�…

Hyperfunction of the mTORC1 pathway has been associated with idiopathic and syndromic
forms of autism spectrum disorder (ASD), including tuberous sclerosis, caused by loss of�…

Autism spectrum disorders (ASD) form a heterogeneous, neurodevelopmental syndrome
characterized by deficits in social interactions and repetitive behavior/restricted interests�…