[HTML][HTML] Insights into the structure and function of the hippocampus: implications for the pathophysiology and treatment of autism spectrum disorder
J Long, H Li, Y Liu, X Liao, Z Tang, K Han…�- Frontiers in�…, 2024 - frontiersin.org
The hippocampus is one of the brain areas affected by autism spectrum disorder (ASD).
Individuals with ASD typically have impairments in hippocampus-dependent learning�…
Individuals with ASD typically have impairments in hippocampus-dependent learning�…
[HTML][HTML] Immune activation during pregnancy exacerbates ASD-related alterations in Shank3-deficient mice
E Atanasova, AP Ar�valo, I Graf, R Zhang, J Bockmann…�- Molecular Autism, 2023 - Springer
Background Autism spectrum disorder (ASD) is mainly characterized by deficits in social
interaction and communication and repetitive behaviors. Known causes of ASD are�…
interaction and communication and repetitive behaviors. Known causes of ASD are�…
[HTML][HTML] Autism Spectrum Disorder: Brain Areas Involved, Neurobiological Mechanisms, Diagnoses and Therapies
J Lamanna, J Meldolesi�- International Journal of Molecular Sciences, 2024 - mdpi.com
Autism spectrum disorder (ASD), affecting over 2% of the pre-school children population,
includes an important fraction of the conditions accounting for the heterogeneity of autism�…
includes an important fraction of the conditions accounting for the heterogeneity of autism�…
[HTML][HTML] Expression profiles of the autism-related SHANK proteins in the human brain
S Woelfle, MT Pedro, J Wagner, M Sch�n, TM Boeckers�- BMC biology, 2023 - Springer
Background SHANKs are major scaffolding proteins at postsynaptic densities (PSDs) in the
central nervous system. Mutations in all three family members have been associated with�…
central nervous system. Mutations in all three family members have been associated with�…
[HTML][HTML] Development of sex- and genotype-specific behavioral phenotypes in a Shank3 mouse model for neurodevelopmental disorders
HF Bauer, JP Delling, J Bockmann…�- Frontiers in Behavioral�…, 2023 - frontiersin.org
Individuals with a SHANK3-related neurodevelopmental disorder, also termed Phelan-
McDermid syndrome or abbreviated as PMS, exhibit significant global developmental delay�…
McDermid syndrome or abbreviated as PMS, exhibit significant global developmental delay�…
[HTML][HTML] Fast and efficient synaptosome isolation and post-synaptic density enrichment from hiPSC-motor neurons by biochemical sub-cellular fractionation
S Rajkumar, TM B�ckers, A Catanese�- STAR protocols, 2023 - Elsevier
We describe here a time-efficient, in-house protocol for synaptosome isolation and
enrichment of the post-synaptic density (PSD) from hiPSC-derived motor neurons. By using�…
enrichment of the post-synaptic density (PSD) from hiPSC-derived motor neurons. By using�…
Impaired erythropoietin‐producing hepatocellular B receptors signaling in the prefrontal cortex and hippocampus following maternal immune activation in male rats
Y Shao, Y Cai, T Chen, K Hao, B Luo…�- Genes, Brain and�…, 2023 - Wiley Online Library
An environmental risk factor for schizophrenia (SZ) is maternal infection, which exerts
longstanding effects on the neurodevelopment of offspring. Accumulating evidence suggests�…
longstanding effects on the neurodevelopment of offspring. Accumulating evidence suggests�…
[HTML][HTML] Non-severe thermal burn injuries induce long-lasting downregulation of gene expression in cortical excitatory neurons and microglia
RCS Ong, JL Beros, K Fuller, FM Wood…�- Frontiers in Molecular�…, 2024 - frontiersin.org
Burn injuries are devastating traumas, often leading to life-long consequences that extend
beyond the observable burn scar. In the context of the nervous system, burn injury patients�…
beyond the observable burn scar. In the context of the nervous system, burn injury patients�…
Microglia and Astrocytes Responses Contribute to Alleviating Inflammatory Damage by Repetitive Transcranial Magnetic Stimulation in Rats with Traumatic Brain�…
FF Qian, RH He, XH Du, Y Wei, Z Zhou, JZ Fan…�- Neurochemical�…, 2024 - Springer
Repetitive transcranial magnetic stimulation (rTMS) is a therapeutic strategy that shows
promise in ameliorating the clinical sequelae following traumatic brain injury (TBI). These�…
promise in ameliorating the clinical sequelae following traumatic brain injury (TBI). These�…
[HTML][HTML] Complex interplay of neurodevelopmental disorders (NDDs), fractures, and osteoporosis: a mendelian randomization study
Z Li, X Wu, H Li, C Bi, C Zhang, Y Sun, Z Yan�- BMC psychiatry, 2024 - Springer
Abstract Background Neurodevelopmental disorders (NDDs), such as Attention-
Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder (ASD), and Tourette�…
Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder (ASD), and Tourette�…