The tracking of lipopolysaccharide through the feto‐maternal compartment and the involvement of maternal TLR4 in inflammation‐induced fetal brain injury

AG Brown, ME Maubert, L Anton…�- American Journal of�…, 2019 - Wiley Online Library
Problem Exposure to intrauterine inflammation (IUI) has been shown to induce fetal brain
injury and increase the risk of acquiring a neurobehavioral disorder. The trafficking of the�…

The maternal autoimmune environment affects the social behavior of offspring

Y Zhang, D Gao, K Kluetzman, A Mendoza…�- Journal of�…, 2013 - Elsevier
Autism spectrum disorders (ASD) are neurodevelopmental disorders with unknown etiology.
BTBR-T+ tf/J (BTBR) mice, a mouse strain with behaviors that resemble autism and with�…

Does microglial dysfunction play a role in autism and Rett syndrome?

I Maezawa, M Calafiore, H Wulff, LW Jin�- Neuron glia biology, 2011 - cambridge.org
Autism spectrum disorders (ASDs) including classic autism is a group of complex
developmental disabilities with core deficits of impaired social interactions, communication�…

Mercury as a hapten: a review of the role of toxicant-induced brain autoantibodies in autism and possible treatment considerations

JK Kern, DA Geier, JA Mehta, KG Homme…�- Journal of Trace�…, 2020 - Elsevier
Background Mercury has many direct and well-recognized neurotoxic effects. However, its
immune effects causing secondary neurotoxicity are less well-recognized. Mercury exposure�…

Peptide sharing between influenza A H1N1 hemagglutinin and human axon guidance proteins

G Lucchese, G Capone, D Kanduc�- Schizophrenia bulletin, 2014 - academic.oup.com
Epidemiologic data suggest that maternal microbial infections may cause fetal
neurodevelopmental disorders, potentially increasing susceptibility to heavy�…

Redefining the role of peripheral LPS as a neuroinflammatory agent and evaluating the role of hydrogen sulphide through metformin intervention

V Tiwari, M Singh, JK Rawat, U Devi, RK Yadav…�- …, 2016 - Springer
Objective The present study was aimed to enumerate the role of metformin-associated H 2 S
release against lipopolysaccharide (LPS) induced neuroinflammation. Materials and�…

[HTML][HTML] Convergence of circuit dysfunction in ASD: a common bridge between diverse genetic and environmental risk factors and common clinical electrophysiology

RG Port, MJ Gandal, TPL Roberts, SJ Siegel…�- Frontiers in cellular�…, 2014 - frontiersin.org
Most recent estimates indicate that 1 in 68 children are affected by an autism spectrum
disorder (ASD). Though decades of research have uncovered much about these disorders�…

Comparative immunogenetics of autism and schizophrenia

BJ Crespi, DL Thiselton�- Genes, Brain and Behavior, 2011 - Wiley Online Library
Autism and schizophrenia are highly heritable neurodevelopmental disorders, each
mediated by a diverse suite of genetic and environmental risk factors. Comorbidity and�…

Autism spectrum disorders: from immunity to behavior

M Careaga, P Ashwood�- Psychoneuroimmunology: Methods and�…, 2012 - Springer
Autism spectrum disorders (ASD) are complex and heterogeneous with a spectrum of
diverse symptoms. Mounting evidence from a number of disciplines suggests a link between�…

Independent maternal and fetal genetic effects on midgestational circulating levels of environmental pollutants

M Traglia, LA Croen, K Lyall…�- G3: Genes�…, 2017 - academic.oup.com
Maternal exposure to environmental pollutants could affect fetal brain development and
increase autism spectrum disorder (ASD) risk in conjunction with differential genetic�…