[HTML][HTML] The role of the immune system in autism spectrum disorder

A Meltzer, J Van de Water�- Neuropsychopharmacology, 2017 - nature.com
Autism is a neurodevelopmental disorder characterized by deficits in communication and
social skills as well as repetitive and stereotypical behaviors. While much effort has focused�…

Consensus paper: pathological role of the cerebellum in autism

SH Fatemi, KA Aldinger, P Ashwood, ML Bauman…�- The Cerebellum, 2012 - Springer
There has been significant advancement in various aspects of scientific knowledge
concerning the role of cerebellum in the etiopathogenesis of autism. In the current�…

Immune mediators in the brain and peripheral tissues in autism spectrum disorder

ML Estes, AK McAllister�- Nature Reviews Neuroscience, 2015 - nature.com
Increasing evidence points to a central role for immune dysregulation in autism spectrum
disorder (ASD). Several ASD risk genes encode components of the immune system and�…

The role of immune dysfunction in the pathophysiology of autism

C Onore, M Careaga, P Ashwood�- Brain, behavior, and immunity, 2012 - Elsevier
Autism spectrum disorders (ASD) are a complex group of neurodevelopmental disorders
encompassing impairments in communication, social interactions and restricted�…

[HTML][HTML] Inflammation and neuro-immune dysregulations in autism spectrum disorders

D Siniscalco, S Schultz, AL Brigida, N Antonucci�- Pharmaceuticals, 2018 - mdpi.com
Autism Spectrum Disorder (ASD) is characterized by persistent deficits in social
communication and interaction and restricted-repetitive patterns of behavior, interests, or�…

[HTML][HTML] Immune dysfunction and autoimmunity as pathological mechanisms in autism spectrum disorders

HK Hughes, E Mills Ko, D Rose…�- Frontiers in cellular�…, 2018 - frontiersin.org
Autism spectrum disorders (ASD) are a group of heterogeneous neurological disorders that
are highly variable and are clinically characterized by deficits in social interactions�…

[HTML][HTML] The cerebellar involvement in autism spectrum disorders: from the social brain to mouse models

L Mapelli, T Soda, E D'Angelo, F Prestori�- International journal of�…, 2022 - mdpi.com
Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders that include
a variety of forms and clinical phenotypes. This heterogeneity complicates the clinical and�…

[HTML][HTML] Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain

S Rose, S Melnyk, O Pavliv, S Bai, TG Nick…�- Translational�…, 2012 - nature.com
Despite increasing evidence of oxidative stress in the pathophysiology of autism, most
studies have not evaluated biomarkers within specific brain regions, and the functional�…

Cytokine dysregulation in autism spectrum disorders (ASD): possible role of the environment

PE Goines, P Ashwood�- Neurotoxicology and teratology, 2013 - Elsevier
Autism spectrum disorders (ASD) are neurodevelopmental diseases that affect an alarming
number of individuals. The etiological basis of ASD is unclear, and evidence suggests it�…

[HTML][HTML] The many roads to mitochondrial dysfunction in neuroimmune and neuropsychiatric disorders

G Morris, M Berk�- BMC medicine, 2015 - Springer
Background Mitochondrial dysfunction and defects in oxidative metabolism are a
characteristic feature of many chronic illnesses not currently classified as mitochondrial�…