PTPN11/Corkscrew activates local presynaptic MAPK signaling to regulate Synapsin, synaptic vesicle pools, and neurotransmission strength, with a dual requirement�…

SN Leahy, DJ Vita, K Broadie�- Journal of Neuroscience, 2024 - Soc Neuroscience
Cytoplasmic protein tyrosine phosphatase nonreceptor type 11 (PTPN11) and Drosophila
homolog Corkscrew (Csw) regulate the mitogen-activated protein kinase (MAPK) pathway�…

MAPK-ERK-CREB signaling pathway upregulates Nav1. 6 in oxaliplatin-induced neuropathic pain in the rat

J Shao, W Yu, W Wei, S Wang, Z Zheng, L Li, Y Sun…�- Toxicology Letters, 2023 - Elsevier
The voltage-gated sodium channel subtype Nav1. 6 is involved in the electrophysiological
changes of primary sensory neurons that occur in oxaliplatin-induced neuropathic pain, but�…

Muscle cofilin alters neuromuscular junction postsynaptic development to strengthen functional neurotransmission

B Christophers, SN Leahy, DB Soffar…�- …, 2024 - journals.biologists.com
Cofilin, an actin severing protein, plays key roles in muscle sarcomere addition and
maintenance. Our previous work found that Drosophila cofilin (DmCFL) muscle knockdown�…

[HTML][HTML] Experience-dependent MAPK/ERK signaling in glia regulates critical period remodeling of synaptic glomeruli

NS Baumann, JC Sears, K Broadie�- Cellular Signalling, 2024 - Elsevier
Early-life critical periods allow initial sensory experience to remodel brain circuitry so that
synaptic connectivity can be optimized to environmental input. In the Drosophila juvenile�…

An incomplete LEOPARD syndrome presented with generalized lentigines.

T Wang, Y Lin, L Sun, L Mao, X Gao…�- Journal of Cosmetic�…, 2024 - search.ebscohost.com
This article discusses a case study of a 24-year-old woman who presented with generalized
lentigines, or brownish macules, on her face, trunk, and extremities. The woman's mother�…