Towards the convergent therapeutic potential of G protein‐coupled receptors in autism spectrum disorders

A Annamneedi, C Gora, A Dudas…�- British journal of�…, 2023 - Wiley Online Library
Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two
core symptoms: deficits in social interaction and communication, and stereotyped�…

[HTML][HTML] Altered motor learning and coordination in mouse models of autism spectrum disorder

KR Cording, HS Bateup�- Frontiers in cellular neuroscience, 2023 - frontiersin.org
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with increasing
prevalence. Over 1,000 risk genes have now been implicated in ASD, suggesting diverse�…

[HTML][HTML] Maternal immune activation induced by prenatal lipopolysaccharide exposure leads to long-lasting autistic-like social, cognitive and immune alterations in�…

E Carbone, V Buzzelli, A Manduca, S Leone…�- International journal of�…, 2023 - mdpi.com
Several studies have supported the association between maternal immune activation (MIA)
caused by exposure to pathogens or inflammation during critical periods of gestation and an�…

Psilocybin mitigates the cognitive deficits observed in a rat model of Fragile X syndrome

V Buzzelli, E Carbone, A Manduca, S Schiavi…�- …, 2023 - Springer
Abstract Rationale Fragile X syndrome (FXS) is the most common form of inherited
intellectual disability (ID) and the leading monogenic cause of autism spectrum disorder�…

[HTML][HTML] FMR1 deletion in rats induces hyperactivity with no changes in striatal dopamine transporter availability

A D'Elia, S Schiavi, A Manduca, A Rava, V Buzzelli…�- Scientific Reports, 2022 - nature.com
Abstract Autism Spectrum Disorder (ASD) is a pervasive neurodevelopmental disorder
emerging in early life characterized by impairments in social interaction, poor verbal and�…

[HTML][HTML] Cannabidiol and positive effects on object recognition memory in an in vivo model of Fragile X Syndrome: Obligatory role of hippocampal GPR55 receptors

A Manduca, V Buzzelli, A Rava, A Feo…�- Pharmacological�…, 2024 - Elsevier
Abstract Cannabidiol (CBD), a non-psychotomimetic constituent of Cannabis sativa, has
been recently approved for epileptic syndromes often associated with Autism spectrum�…

Cannabinoid treatment for the symptoms of autism spectrum disorder

A Aran, D Cayam Rand�- Expert Opinion on Emerging Drugs, 2024 - Taylor & Francis
Introduction Autism spectrum disorder (ASD) is a neurodevelopmental disorder affecting
approximately 3% of school-age children. The core symptoms are deficits in social�…

Cannabidiol improves maternal obesity-induced behavioral, neuroinflammatory and neurochemical dysfunctions in the juvenile offspring

F da Silva Rodrigues, J Jantsch…�- Brain, Behavior, and�…, 2024 - Elsevier
Maternal obesity is associated with an increased risk of psychiatric disorders such as
anxiety, depression, schizophrenia and autism spectrum disorder in the offspring. While�…

[HTML][HTML] Unraveling the Endocannabinoid System: Exploring Its Therapeutic Potential in Autism Spectrum Disorder

A Jana, A Nath, P Sen, S Kundu, BS Alghamdi…�- NeuroMolecular�…, 2024 - Springer
The salient features of autism spectrum disorder (ASD) encompass persistent difficulties in
social communication, as well as the presence of restricted and repetitive facets of behavior�…

Safety and efficacy of orally administered full-spectrum medicinal cannabis plant extract 0.08% THC (NTI-164) in children with autism spectrum disorder: An open�…

D El-Sukkari, KG Sharma, B Fleiss, D Bragazna…�- medRxiv, 2023 - medrxiv.org
Autism spectrum disorder (ASD) is commonly associated with debilitating comorbidities
impacting the well-being of affected children and their families. Some children with ASD�…