It is estimated that, at minimum, 500 million individuals suffer from cellular metabolic
dysfunction, such as diabetes mellitus (DM), throughout the world. Even more concerning is�…

Almost three million individuals suffer from multiple sclerosis (MS) throughout the world, a
demyelinating disease in the nervous system with increased prevalence over the last five�…

Disorders of metabolism affect multiple systems throughout the body, but may have the
greatest impact on both central and peripheral nervous systems. Current available�…

Life expectancy is increasing throughout the world and coincides with a rise in non-
communicable diseases (NCDs), especially for metabolic disease that includes diabetes�…

As a significant non-communicable disease, cardiovascular disease is the leading cause of
death for both men and women, comprises almost twenty percent of deaths in most racial�…

Abstract Aims Dysregulation of PI3K/Akt/GSK3β signaling has been implicated in various
neurological disorders, including autism spectrum disorder (ASD). G protein-coupled�…

Autistic spectrum disease (ASD) is an increasingly common diagnosis nowadays with a
prevalence of 1–2% in most countries. Its complex causality—a combination of genetic�…

Iron metabolism in the body is a critical process for sustaining life as well as determining cell
fate [1-4]. As an essential element, iron in the ferrous state (Fe2+) is an electron donor but in�…

Metabolic disorders and diabetes (DM) impact more than five hundred million individuals
throughout the world and are insidious in onset, chronic in nature, and yield significant�…

Involving 1 million people a year, suicide represents one of the major topics of psychiatric
research. Despite the focus in recent years on neurobiological underpinnings�…