[HTML][HTML] RNA modifications and RNA metabolism in neurological disease pathogenesis
B Chatterjee, CKJ Shen, P Majumder�- International journal of molecular�…, 2021 - mdpi.com
The intrinsic cellular heterogeneity and molecular complexity of the mammalian nervous
system relies substantially on the dynamic nature and spatiotemporal patterning of gene�…
system relies substantially on the dynamic nature and spatiotemporal patterning of gene�…
[HTML][HTML] The epitranscriptomic mechanism of metal toxicity and carcinogenesis
Metals are common toxic environmental pollutants. Acute or chronic exposure to metal
pollutants causes severe adverse health effects in animals and humans, such as�…
pollutants causes severe adverse health effects in animals and humans, such as�…
[HTML][HTML] METTL3 suppresses neuropathic pain via modulating N6-methyladenosine-dependent primary miR-150 processing
L Zhang, X Zhao, J Wang, Y Jin, M Gong, Y Ye…�- Cell death�…, 2022 - nature.com
Abstract Methyltransferase-like 3 (METTL3)-modulated N6-methyladenosine (m6A) was
recently identified as an important epigenetic regulation type during RNA processing and�…
recently identified as an important epigenetic regulation type during RNA processing and�…
Amentoflavone and methyl hesperidin, novel lead molecules targeting epitranscriptomic modulator in acute myeloid leukemia: In silico drug screening and molecular�…
S Manna, P Samal, R Basak, A Mitra, AK Roy…�- Journal of Molecular�…, 2023 - Springer
Introduction M6A modification in transcriptome is critical in regulating different cellular
processes, including cancer. In human beings, METTL3 is the major m6A writer that works in�…
processes, including cancer. In human beings, METTL3 is the major m6A writer that works in�…
[HTML][HTML] The potential role of RNA modification in skin diseases, as well as the recent advances in its detection methods and therapeutic agents
Y Yu, C Liang, X Wang, Y Shi, L Shen�- Biomedicine & Pharmacotherapy, 2023 - Elsevier
RNA modification is considered as an epigenetic modification that plays an indispensable
role in biological processes such as gene expression and genome editing without altering�…
role in biological processes such as gene expression and genome editing without altering�…
N6-methyladenosine modifications of mRNAs and long noncoding RNAs in oxygen-induced retinopathy in mice
Y Peng, Z Wang, B Li, W Tan, J Zou, Y Li…�- Experimental Eye�…, 2022 - Elsevier
Retinal neovascular diseases are major causes of blindness worldwide. As a common
epitranscriptomic modification of eukaryotic RNAs, N 6-methyladenosine (m 6 A) is�…
epitranscriptomic modification of eukaryotic RNAs, N 6-methyladenosine (m 6 A) is�…
[HTML][HTML] Dynamic m6A-ncRNAs association and their impact on cancer pathogenesis, immune regulation and therapeutic response
Y Yan, J Peng, Q Liang, X Ren, Y Cai, B Peng, X Chen…�- Genes & diseases, 2023 - Elsevier
Several types of modifications have been proven to participate in the metabolism and
processing of different RNA types, including non-coding RNAs (ncRNAs). N-6�…
processing of different RNA types, including non-coding RNAs (ncRNAs). N-6�…
Identification of epigenetically active L1 promoters in the human brain and their relationship with psychiatric disorders
R Watanabe, Y Nakachi, H Matsubara, J Ueda…�- Neuroscience�…, 2023 - Elsevier
Long interspersed nuclear element-1 (LINE-1, L1) affects the transcriptome landscape in
multiple ways. Promoter activity within its 5'UTR plays a critical role in regulating diverse L1�…
multiple ways. Promoter activity within its 5'UTR plays a critical role in regulating diverse L1�…
[HTML][HTML] Expression profiling of N6-methyladenosine-modified mRNA in PC12 cells in response to unconjugated bilirubin
J Zhou, S Liao, C Zhang, J Luo, G Li, H Li�- Molecular Biology Reports, 2023 - Springer
Background Abnormal methylation of N 6-methyladenosine (m6A) is reportedly associated
with central nervous system disorders. However, the role of m6A mRNA methylation in�…
with central nervous system disorders. However, the role of m6A mRNA methylation in�…
[HTML][HTML] Salsolinol as an RNA m6A methylation inducer mediates dopaminergic neuronal death by regulating YAP1 and autophagy
J Wang, Y Ran, Z Li, T Zhao, F Zhang…�- Neural Regeneration�…, 2025 - journals.lww.com
Abstract Salsolinol (1-methyl-6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline, Sal) is a
catechol isoquinoline that causes neurotoxicity and shares structural similarity with 1-methyl�…
catechol isoquinoline that causes neurotoxicity and shares structural similarity with 1-methyl�…