[HTML][HTML] RNA modifications and RNA metabolism in neurological disease pathogenesis

B Chatterjee, CKJ Shen, P Majumder�- International journal of molecular�…, 2021 - mdpi.com
The intrinsic cellular heterogeneity and molecular complexity of the mammalian nervous
system relies substantially on the dynamic nature and spatiotemporal patterning of gene�…

[HTML][HTML] The epitranscriptomic mechanism of metal toxicity and carcinogenesis

C Yang, Z Wang�- International Journal of Molecular Sciences, 2022 - mdpi.com
Metals are common toxic environmental pollutants. Acute or chronic exposure to metal
pollutants causes severe adverse health effects in animals and humans, such as�…

[HTML][HTML] METTL3 suppresses neuropathic pain via modulating N6-methyladenosine-dependent primary miR-150 processing

L Zhang, X Zhao, J Wang, Y Jin, M Gong, Y Ye…�- Cell death�…, 2022 - nature.com
Abstract Methyltransferase-like 3 (METTL3)-modulated N6-methyladenosine (m6A) was
recently identified as an important epigenetic regulation type during RNA processing and�…

Amentoflavone and methyl hesperidin, novel lead molecules targeting epitranscriptomic modulator in acute myeloid leukemia: In silico drug screening and molecular�…

S Manna, P Samal, R Basak, A Mitra, AK Roy…�- Journal of Molecular�…, 2023 - Springer
Introduction M6A modification in transcriptome is critical in regulating different cellular
processes, including cancer. In human beings, METTL3 is the major m6A writer that works in�…

[HTML][HTML] The potential role of RNA modification in skin diseases, as well as the recent advances in its detection methods and therapeutic agents

Y Yu, C Liang, X Wang, Y Shi, L Shen�- Biomedicine & Pharmacotherapy, 2023 - Elsevier
RNA modification is considered as an epigenetic modification that plays an indispensable
role in biological processes such as gene expression and genome editing without altering�…

N6-methyladenosine modifications of mRNAs and long noncoding RNAs in oxygen-induced retinopathy in mice

Y Peng, Z Wang, B Li, W Tan, J Zou, Y Li…�- Experimental Eye�…, 2022 - Elsevier
Retinal neovascular diseases are major causes of blindness worldwide. As a common
epitranscriptomic modification of eukaryotic RNAs, N 6-methyladenosine (m 6 A) is�…

[HTML][HTML] Dynamic m6A-ncRNAs association and their impact on cancer pathogenesis, immune regulation and therapeutic response

Y Yan, J Peng, Q Liang, X Ren, Y Cai, B Peng, X Chen…�- Genes & diseases, 2023 - Elsevier
Several types of modifications have been proven to participate in the metabolism and
processing of different RNA types, including non-coding RNAs (ncRNAs). N-6�…

Identification of epigenetically active L1 promoters in the human brain and their relationship with psychiatric disorders

R Watanabe, Y Nakachi, H Matsubara, J Ueda…�- Neuroscience�…, 2023 - Elsevier
Long interspersed nuclear element-1 (LINE-1, L1) affects the transcriptome landscape in
multiple ways. Promoter activity within its 5'UTR plays a critical role in regulating diverse L1�…

[HTML][HTML] Expression profiling of N6-methyladenosine-modified mRNA in PC12 cells in response to unconjugated bilirubin

J Zhou, S Liao, C Zhang, J Luo, G Li, H Li�- Molecular Biology Reports, 2023 - Springer
Background Abnormal methylation of N 6-methyladenosine (m6A) is reportedly associated
with central nervous system disorders. However, the role of m6A mRNA methylation in�…

[HTML][HTML] Salsolinol as an RNA m6A methylation inducer mediates dopaminergic neuronal death by regulating YAP1 and autophagy

J Wang, Y Ran, Z Li, T Zhao, F Zhang…�- Neural Regeneration�…, 2025 - journals.lww.com
Abstract Salsolinol (1-methyl-6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline, Sal) is a
catechol isoquinoline that causes neurotoxicity and shares structural similarity with 1-methyl�…