[HTML][HTML] Dysregulation of GABAergic signaling in neurodevelomental disorders: targeting cation-chloride co-transporters to re-establish a proper E/I balance
The construction of the brain relies on a series of well-defined genetically and experience-or
activity-dependent mechanisms which allow to adapt to the external environment. Disruption�…
activity-dependent mechanisms which allow to adapt to the external environment. Disruption�…
The epilepsy–autism spectrum disorder phenotype in the era of molecular genetics and precision therapy
N Specchio, V Di Micco, M Trivisano, A Ferretti…�- …, 2022 - Wiley Online Library
Autism spectrum disorder (ASD) is frequently associated with infants with epileptic
encephalopathy, and early interventions targeting social and cognitive deficits can have�…
encephalopathy, and early interventions targeting social and cognitive deficits can have�…
Shared etiology in autism spectrum disorder and epilepsy with functional disability
A Zahra, YF Wang, Q Wang, J Wu�- Behavioural Neurology, 2022 - Wiley Online Library
Autism spectrum disorders and epilepsies are heterogeneous human disorders that have
miscellaneous etiologies and pathophysiology. There is considerable risk of frequent�…
miscellaneous etiologies and pathophysiology. There is considerable risk of frequent�…
Mice lacking full length Adgrb1 (Bai1) exhibit social deficits, increased seizure susceptibility, and altered brain development
The adhesion G protein-coupled receptor BAI1/ADGRB1 plays an important role in
suppressing angiogenesis, mediating phagocytosis, and acting as a brain tumor suppressor�…
suppressing angiogenesis, mediating phagocytosis, and acting as a brain tumor suppressor�…
[HTML][HTML] “Neural Noise” in Auditory Responses in Young Autistic and Neurotypical Children
Elevated “neural noise” has been advanced as an explanation of autism and autistic
sensory experiences. However, functional neuroimaging measures of neural noise may be�…
sensory experiences. However, functional neuroimaging measures of neural noise may be�…
[HTML][HTML] Autism with epilepsy: a neuropsychopharmacology update
R Canitano, R Palumbi, V Scandurra�- Genes, 2022 - mdpi.com
The association between autism spectrum disorders (ASD) and epilepsy has been
extensively documented, and the estimated prevalence varies depending upon the selected�…
extensively documented, and the estimated prevalence varies depending upon the selected�…
[HTML][HTML] Audiogenic Seizures and Social Deficits: No Aggravation Found in Krushinsky–Molodkina Rats
A Rebik, N Broshevitskaya, S Kuzhuget, P Aleksandrov…�- Biomedicines, 2023 - mdpi.com
Epilepsy or epileptic syndromes affect more than 70 million people, often comorbid with
autism spectrum disorders (ASD). Seizures are concerned as a factor for social regression in�…
autism spectrum disorders (ASD). Seizures are concerned as a factor for social regression in�…
[HTML][HTML] Seizure susceptibility to various convulsant stimuli in the BTBR mouse model of autism spectrum disorders
Background: Autism spectrum disorders (ASDs) are one of the most severe chronic
childhood disorders in terms of prevalence, morbidity, and impact on society. Interestingly�…
childhood disorders in terms of prevalence, morbidity, and impact on society. Interestingly�…
[HTML][HTML] Autism Spectrum Disorder with Epilepsy: A Research Protocol for a Clinical and Genetic Study
R Canitano, Y Bozzi�- Genes, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a common neurodevelopmental condition affecting~ 1%
of people worldwide. Core ASD features present with impaired social communication�…
of people worldwide. Core ASD features present with impaired social communication�…
[HTML][HTML] Pathophysiology to Risk Factor and Therapeutics to Treatment Strategies on Epilepsy
APA Boleti, PHO Cardoso, BEF Frihling…�- Brain Sciences, 2024 - mdpi.com
Epilepsy represents a condition in which abnormal neuronal discharges or the
hyperexcitability of neurons occur with synchronicity, presenting a significant public health�…
hyperexcitability of neurons occur with synchronicity, presenting a significant public health�…