[HTML][HTML] Dysregulation of GABAergic signaling in neurodevelomental disorders: targeting cation-chloride co-transporters to re-establish a proper E/I balance

E Cherubini, G Di Cristo, M Avoli�- Frontiers in cellular neuroscience, 2022 - frontiersin.org
The construction of the brain relies on a series of well-defined genetically and experience-or
activity-dependent mechanisms which allow to adapt to the external environment. Disruption�…

The epilepsy–autism spectrum disorder phenotype in the era of molecular genetics and precision therapy

N Specchio, V Di Micco, M Trivisano, A Ferretti…�- …, 2022 - Wiley Online Library
Autism spectrum disorder (ASD) is frequently associated with infants with epileptic
encephalopathy, and early interventions targeting social and cognitive deficits can have�…

Shared etiology in autism spectrum disorder and epilepsy with functional disability

A Zahra, YF Wang, Q Wang, J Wu�- Behavioural Neurology, 2022 - Wiley Online Library
Autism spectrum disorders and epilepsies are heterogeneous human disorders that have
miscellaneous etiologies and pathophysiology. There is considerable risk of frequent�…

Mice lacking full length Adgrb1 (Bai1) exhibit social deficits, increased seizure susceptibility, and altered brain development

FH Shiu, JC Wong, T Yamamoto, T Lala…�- Experimental�…, 2022 - Elsevier
The adhesion G protein-coupled receptor BAI1/ADGRB1 plays an important role in
suppressing angiogenesis, mediating phagocytosis, and acting as a brain tumor suppressor�…

[HTML][HTML] “Neural Noise” in Auditory Responses in Young Autistic and Neurotypical Children

P Dwyer, S Vukusic, ZJ Williams, CD Saron…�- Journal of autism and�…, 2024 - Springer
Elevated “neural noise” has been advanced as an explanation of autism and autistic
sensory experiences. However, functional neuroimaging measures of neural noise may be�…

[HTML][HTML] Autism with epilepsy: a neuropsychopharmacology update

R Canitano, R Palumbi, V Scandurra�- Genes, 2022 - mdpi.com
The association between autism spectrum disorders (ASD) and epilepsy has been
extensively documented, and the estimated prevalence varies depending upon the selected�…

[HTML][HTML] Audiogenic Seizures and Social Deficits: No Aggravation Found in Krushinsky–Molodkina Rats

A Rebik, N Broshevitskaya, S Kuzhuget, P Aleksandrov…�- Biomedicines, 2023 - mdpi.com
Epilepsy or epileptic syndromes affect more than 70 million people, often comorbid with
autism spectrum disorders (ASD). Seizures are concerned as a factor for social regression in�…

[HTML][HTML] Seizure susceptibility to various convulsant stimuli in the BTBR mouse model of autism spectrum disorders

M Tallarico, A Leo, E Russo, R Citraro…�- Frontiers in�…, 2023 - frontiersin.org
Background: Autism spectrum disorders (ASDs) are one of the most severe chronic
childhood disorders in terms of prevalence, morbidity, and impact on society. Interestingly�…

[HTML][HTML] Autism Spectrum Disorder with Epilepsy: A Research Protocol for a Clinical and Genetic Study

R Canitano, Y Bozzi�- Genes, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a common neurodevelopmental condition affecting~ 1%
of people worldwide. Core ASD features present with impaired social communication�…

[HTML][HTML] Pathophysiology to Risk Factor and Therapeutics to Treatment Strategies on Epilepsy

APA Boleti, PHO Cardoso, BEF Frihling…�- Brain Sciences, 2024 - mdpi.com
Epilepsy represents a condition in which abnormal neuronal discharges or the
hyperexcitability of neurons occur with synchronicity, presenting a significant public health�…