The immune-inflammatory response is associated with increased nitro-oxidative stress. The
aim of this mechanistic review is to examine:(a) the role of redox-sensitive transcription�…

Over the past two decades, compelling evidence has emerged indicating that immune
mechanisms can contribute to the pathogenesis of major depressive disorder (MDD) and�…

Recent advances in vitamin D research indicate that this vitamin, a secosteroid hormone,
has beneficial effects on several body systems other than the musculoskeletal system. Both�…

Mental illness, including depression, anxiety and bipolar disorder, accounts for a significant
proportion of global disability and poses a substantial social, economic and heath burden�…

Epidemiological evidence indicates the presence of dysregulated homeostatic biological
pathways in depressed patients, such as increased inflammation and disrupted energy�…

Vitamin D deficiency has been linked to the onset of diabetes. This review summarizes the
role of Vitamin D in maintaining the normal release of insulin by the pancreatic beta cells (β�…

Autism spectrum disorder (ASD) is a neurodevelopmental disease that is characterized by a
deficit in social interactions and communication, as well as repetitive and restrictive�…

Background: Persistent low-grade immune-inflammatory processes, oxidative and
nitrosative stress (O&NS), and hypothalamic-pituitary-adrenal axis activation are integral to�…

Autism spectrum disorder (ASD) affects~ 2% of children in the United States. The etiology of
ASD likely involves environmental factors triggering physiological abnormalities in�…

There is a growing awareness that gut commensal metabolites play a major role in host
physiology and indeed the pathophysiology of several illnesses. The composition of the�…