Advancing the understanding of autism disease mechanisms through genetics

L de la Torre-Ubieta, H Won, JL Stein…�- Nature medicine, 2016 - nature.com
Progress in understanding the genetic etiology of autism spectrum disorders (ASD) has
fueled remarkable advances in our understanding of its potential neurobiological�…

Maternal immune activation and autism spectrum disorder: from rodents to nonhuman and human primates

M Careaga, T Murai, MD Bauman�- Biological psychiatry, 2017 - Elsevier
A subset of women who are exposed to infection during pregnancy have an increased risk of
giving birth to a child who will later be diagnosed with a neurodevelopmental or�…

[HTML][HTML] MacaquePose: a novel “in the wild” macaque monkey pose dataset for markerless motion capture

R Labuguen, J Matsumoto, SB Negrete…�- Frontiers in behavioral�…, 2021 - frontiersin.org
Video-based markerless motion capture permits quantification of an animal's pose and
motion, with a high spatiotemporal resolution in a naturalistic context, and is a powerful tool�…

Multiple anesthetic exposure in infant monkeys alters emotional reactivity to an acute stressor

J Raper, MC Alvarado, KL Murphy, MG Baxter�- Anesthesiology, 2015 - pubs.asahq.org
Background Retrospective studies in humans have shown a higher prevalence of learning
disabilities in children that received multiple exposures to general anesthesia before the age�…

[HTML][HTML] Maternal valproic acid exposure leads to neurogenesis defects and autism-like behaviors in non-human primates

H Zhao, Q Wang, T Yan, Y Zhang, H Xu, H Yu…�- Translational�…, 2019 - nature.com
Despite the substantial progress made in identifying genetic defects in autism spectrum
disorder (ASD), the etiology for majority of ASD individuals remains elusive. Maternal�…

In vivo characterization of alveolar and interstitial lung macrophages in rhesus macaques: implications for understanding lung disease in humans

Y Cai, C Sugimoto, M Arainga, X Alvarez…�- The Journal of�…, 2014 - journals.aai.org
Alveolar macrophages (AMs) obtained by bronchoalveolar lavage (BAL) are commonly
used to study lung macrophage-mediated immune responses. Questions remain, however�…

[HTML][HTML] Zebrafish modeling of autism spectrum disorders, current status and future prospective

A Tayanloo-Beik, SK Hamidpour, M Abedi…�- Frontiers in�…, 2022 - frontiersin.org
Autism spectrum disorder (ASD) refers to a complicated range of childhood
neurodevelopmental disorders which can occur via genetic or non-genetic factors. Clinically�…

Prenatal Zika virus infection has sex-specific effects on infant physical development and mother-infant social interactions

G Moadab, F Pittet, JL Bennett, CL Taylor…�- Science Translational�…, 2023 - science.org
There is enormous variation in the extent to which fetal Zika virus (fZIKV) infection affects the
developing brain. Despite the neural consequences of fZIKV infection observed in people�…

[HTML][HTML] Genomics in neurodevelopmental disorders: an avenue to personalized medicine

DC Tărlungeanu, G Novarino�- Experimental & molecular medicine, 2018 - nature.com
Despite the remarkable number of scientific breakthroughs of the last 100 years, the
treatment of neurodevelopmental disorders (eg, autism spectrum disorder, intellectual�…

[HTML][HTML] Maternal antibodies from mothers of children with autism alter brain growth and social behavior development in the rhesus monkey

MD Bauman, AM Iosif, P Ashwood…�- Translational�…, 2013 - nature.com
Antibodies directed against fetal brain proteins of 37 and 73 kDa molecular weight are found
in approximately 12% of mothers who have children with autism spectrum disorder (ASD)�…