Advancing the understanding of autism disease mechanisms through genetics
Progress in understanding the genetic etiology of autism spectrum disorders (ASD) has
fueled remarkable advances in our understanding of its potential neurobiological�…
fueled remarkable advances in our understanding of its potential neurobiological�…
Maternal immune activation and autism spectrum disorder: from rodents to nonhuman and human primates
A subset of women who are exposed to infection during pregnancy have an increased risk of
giving birth to a child who will later be diagnosed with a neurodevelopmental or�…
giving birth to a child who will later be diagnosed with a neurodevelopmental or�…
[HTML][HTML] MacaquePose: a novel “in the wild” macaque monkey pose dataset for markerless motion capture
R Labuguen, J Matsumoto, SB Negrete…�- Frontiers in behavioral�…, 2021 - frontiersin.org
Video-based markerless motion capture permits quantification of an animal's pose and
motion, with a high spatiotemporal resolution in a naturalistic context, and is a powerful tool�…
motion, with a high spatiotemporal resolution in a naturalistic context, and is a powerful tool�…
Multiple anesthetic exposure in infant monkeys alters emotional reactivity to an acute stressor
Background Retrospective studies in humans have shown a higher prevalence of learning
disabilities in children that received multiple exposures to general anesthesia before the age�…
disabilities in children that received multiple exposures to general anesthesia before the age�…
[HTML][HTML] Maternal valproic acid exposure leads to neurogenesis defects and autism-like behaviors in non-human primates
H Zhao, Q Wang, T Yan, Y Zhang, H Xu, H Yu…�- Translational�…, 2019 - nature.com
Despite the substantial progress made in identifying genetic defects in autism spectrum
disorder (ASD), the etiology for majority of ASD individuals remains elusive. Maternal�…
disorder (ASD), the etiology for majority of ASD individuals remains elusive. Maternal�…
In vivo characterization of alveolar and interstitial lung macrophages in rhesus macaques: implications for understanding lung disease in humans
Alveolar macrophages (AMs) obtained by bronchoalveolar lavage (BAL) are commonly
used to study lung macrophage-mediated immune responses. Questions remain, however�…
used to study lung macrophage-mediated immune responses. Questions remain, however�…
[HTML][HTML] Zebrafish modeling of autism spectrum disorders, current status and future prospective
A Tayanloo-Beik, SK Hamidpour, M Abedi…�- Frontiers in�…, 2022 - frontiersin.org
Autism spectrum disorder (ASD) refers to a complicated range of childhood
neurodevelopmental disorders which can occur via genetic or non-genetic factors. Clinically�…
neurodevelopmental disorders which can occur via genetic or non-genetic factors. Clinically�…
Prenatal Zika virus infection has sex-specific effects on infant physical development and mother-infant social interactions
There is enormous variation in the extent to which fetal Zika virus (fZIKV) infection affects the
developing brain. Despite the neural consequences of fZIKV infection observed in people�…
developing brain. Despite the neural consequences of fZIKV infection observed in people�…
[HTML][HTML] Genomics in neurodevelopmental disorders: an avenue to personalized medicine
DC Tărlungeanu, G Novarino�- Experimental & molecular medicine, 2018 - nature.com
Despite the remarkable number of scientific breakthroughs of the last 100 years, the
treatment of neurodevelopmental disorders (eg, autism spectrum disorder, intellectual�…
treatment of neurodevelopmental disorders (eg, autism spectrum disorder, intellectual�…
[HTML][HTML] Maternal antibodies from mothers of children with autism alter brain growth and social behavior development in the rhesus monkey
Antibodies directed against fetal brain proteins of 37 and 73 kDa molecular weight are found
in approximately 12% of mothers who have children with autism spectrum disorder (ASD)�…
in approximately 12% of mothers who have children with autism spectrum disorder (ASD)�…