[HTML][HTML] Treatment of overdose in the synthetic opioid era
P Skolnick�- Pharmacology & therapeutics, 2022 - Elsevier
Overdose deaths are often viewed as the leading edge of the opioid epidemic which has
gripped the United States over the past two decades (Skolnick, 2018a). This emphasis is�…
gripped the United States over the past two decades (Skolnick, 2018a). This emphasis is�…
[HTML][HTML] Estimating naloxone need in the USA across fentanyl, heroin, and prescription opioid epidemics: a modelling study
Background The US overdose crisis is driven by fentanyl, heroin, and prescription opioids.
One evidence-based policy response has been to broaden naloxone distribution, but how�…
One evidence-based policy response has been to broaden naloxone distribution, but how�…
Trends in drug overdose deaths among US adolescents, January 2010 to June 2021
Methods| We calculated drug overdose deaths per 100 000 population for adolescents
(aged 14-18 years), compared with the overall population, from January 2010 to June 2021�…
(aged 14-18 years), compared with the overall population, from January 2010 to June 2021�…
Implementation of safe supply alternatives during intersecting COVID-19 and overdose health emergencies in British Columbia, Canada, 2021
Objectives. To explore the implementation and effectiveness of the British Columbia,
Canada, risk mitigation guidelines among people who use drugs, focusing on how�…
Canada, risk mitigation guidelines among people who use drugs, focusing on how�…
Spatiotemporal analysis exploring the effect of law enforcement drug market disruptions on overdose, Indianapolis, Indiana, 2020–2021
Objectives. To test the hypothesis that law enforcement efforts to disrupt local drug markets
by seizing opioids or stimulants are associated with increased spatiotemporal clustering of�…
by seizing opioids or stimulants are associated with increased spatiotemporal clustering of�…
Charting the fourth wave: Geographic, temporal, race/ethnicity and demographic trends in polysubstance fentanyl overdose deaths in the United States, 2010–2021
J Friedman, CL Shover�- Addiction, 2023 - Wiley Online Library
Aims To characterize polysubstance death in the United States during the transition to the
fourth wave of the drug overdose crisis. To characterize co‐involved substances in fatal�…
fourth wave of the drug overdose crisis. To characterize co‐involved substances in fatal�…
Buprenorphine versus methadone for the treatment of opioid dependence: a systematic review and meta-analysis of randomised and observational studies
L Degenhardt, B Clark, G Macpherson…�- The Lancet�…, 2023 - thelancet.com
Background Opioid dependence is associated with substantial health and social burdens,
and opioid agonist treatment (OAT) is highly effective in improving multiple outcomes for�…
and opioid agonist treatment (OAT) is highly effective in improving multiple outcomes for�…
Association of methamphetamine and opioid use with nonfatal overdose in rural communities
Importance Overdoses continue to increase in the US, but the contribution of
methamphetamine use is understudied in rural communities. Objective To estimate the�…
methamphetamine use is understudied in rural communities. Objective To estimate the�…
[HTML][HTML] Overdose mortality rates for opioids and stimulant drugs are substantially higher in men than in women: state-level analysis
ER Butelman, Y Huang, DH Epstein…�- …, 2023 - nature.com
Drug overdoses from opioids and stimulants are a major cause of mortality in the United
States. It is unclear if there are stable sex differences in overdose mortality for these drugs�…
States. It is unclear if there are stable sex differences in overdose mortality for these drugs�…
Reducing opioid use disorder and overdose deaths in the United States: a dynamic modeling analysis
EJ Stringfellow, TY Lim, K Humphreys…�- Science�…, 2022 - science.org
Opioid overdose deaths remain a major public health crisis. We used a system dynamics
simulation model of the US opioid-using population age 12 and older to explore the impacts�…
simulation model of the US opioid-using population age 12 and older to explore the impacts�…