Autism is a severe neurobehavioral syndrome, arising largely as an inherited disorder,
which can arise from several diseases. Despite recent advances in identifying some genes�…

We review research evidence on the emergence and development of active “self-and-other”
awareness in infancy, and examine the importance of its motives and emotions to mental�…

Objective: To quantify developmental abnormalities in cerebral and cerebellar volume in
autism. Methods: The authors studied 60 autistic and 52 normal boys (age, 2 to 16 years)�…

The aims of this longitudinal study were:(1) to assess the continuity and change in
diagnosis, intelligence, and language skills in children with autism, Down syndrome, and�…

This new edition of the biology of the Autistic Syndromes provides a comprehensive update
on recent advances in this rapidly developing field. It is designed for use by physicians who�…

The social motivation hypothesis of autism posits that infants with autism do not experience
social stimuli as rewarding, thereby leading to a cascade of potentially negative�…

Metabolic, functional, behavioral, and histologic studies suggest that the structure of the
cerebrum may be abnormal in autism. In a previous cross-sectional study we found�…

Deficits in language are a core feature of autism. The superior temporal gyrus (STG) is
involved in auditory processing, including language, but also has been implicated as a�…

Recent evidence supports a role for genetics in autism, but other findings are difficult to
reconcile with a purely genetic cause. Pathological changes in the cerebellum in autism are�…

The cerebellum has traditionally been seen primarily to coordinate voluntary movement, but
evidence is accumulating that it may play a role in cognition and behavior as well. This is a�…