[HTML][HTML] Single-cell and spatial multi-omics in the plant sciences: Technical advances, applications, and perspectives

X Yu, Z Liu, X Sun�- Plant communications, 2023 - cell.com
Plants contain a large number of cell types and exhibit complex regulatory mechanisms.
Studies at the single-cell level have gradually become more common in plant science�…

Integrative metabolomics science in Alzheimer's disease: relevance and future perspectives

S Lista, R Gonz�lez-Dom�nguez, S L�pez-Ortiz…�- Ageing Research�…, 2023 - Elsevier
Alzheimer's disease (AD) is determined by various pathophysiological mechanisms starting
10–25 years before the onset of clinical symptoms. As multiple functionally interconnected�…

Desorption Electrospray Ionization Mass Spectrometry Imaging (DESI-MSI) in Disease Diagnosis: An Overview.

BS Kumar�- Analytical Methods, 2023 - pubs.rsc.org
Tissue analysis, which is essential to histology and is considered the benchmark for the
diagnosis and prognosis of many illnesses, including cancer, is significant. During surgery�…

Metabolomics-based mass spectrometry methods to analyze the chemical content of 3D organoid models

SE Murphy, JV Sweedler�- Analyst, 2022 - pubs.rsc.org
Metabolomics, the study of metabolites present in biological samples, can provide a global
view of sample state as well as insights into biological changes caused by disease or�…

Mass spectrometry imaging: new eyes on natural products for drug research and development

J Hou, Z Zhang, W Wu, Q He, T Zhang, Y Liu…�- Acta Pharmacologica�…, 2022 - nature.com
Natural products (NPs) and their structural analogs represent a major source of novel drug
development for disease prevention and treatment. The development of new drugs from NPs�…

Recent development and applications of ambient mass spectrometry imaging in pharmaceutical research: An overview

BS Kumar�- Analytical Methods, 2023 - pubs.rsc.org
The application of ambient mass spectrometry imaging “MSI” is expanding in the areas of
fundamental research on drug delivery and multiple phases of the process of identifying and�…

[HTML][HTML] Sensing of Catecholamine in Human Urine Using a Simple Colorimetric Assay Based on Direct Melanochrome and Indolequinone Formation

M Lettieri, M Spinelli, L Caponi, S Scarano, P Palladino…�- Sensors, 2023 - mdpi.com
We used the first enzyme-free synthesis and stabilization of soluble melanochrome (MC)
and 5, 6-indolequinone (IQ) derived from levodopa (LD), dopamine (DA), and�…

[PDF][PDF] Advances and applications of mass spectrometry imaging in neuroscience: An overview

BS Kumar�- Mass Spectrom. Lett, 2023 - koreascience.kr
Understanding the chemical composition of the brain helps researchers comprehend
various neurological processes effectively. Understanding of the fundamental pathological�…

A companion to the preclinical common data elements for proteomics, lipidomics, and metabolomics data in rodent epilepsy models. A report of the TASK3‐WG4�…

L Bindila, T Eid, JD Mills, MS Hildebrand…�- Epilepsia�…, 2022 - Wiley Online Library
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES)
Joint Translational Task Force established the TASK3 working groups to create common�…

[HTML][HTML] 基质辅助激光解吸电离-质谱成像技术 (MALDI-MSI) 及其在脑神经性疾病研究中的应用

金涛, 潘本松, 聂洪港�- 计量科学与技术, 2022 - jlkj.nim.ac.cn
大脑是人体内结构最精细, 功能最复杂的高级器官, 其化学物质种类众多, 功能多样,
作用机制复杂. 研究证明, 脑中枢神经系统疾病的病变脑组织都涉及到一些神经分子的改变�…