The prefrontal cortex (PFC) has emerged as one of the regions most consistently impaired in
major depressive disorder (MDD). Although functional and structural PFC abnormalities�…

Effective motor performance is important for surviving and thriving, and skilled movement is
critical in many activities. Much theorizing over the past few decades has focused on how�…

The ability to adaptively regulate emotion is essential for mental and physical well-being.
How should we organize the myriad ways people attempt to regulate their emotions? We�…

Background: Placebo and nocebo effects occur in clinical or laboratory medical contexts
after administration of an inert treatment or as part of active treatments and are due to�…

Long-standing social problems such as poor achievement, personal and intergroup conflict,
bad health, and unhappiness can seem like permanent features of the social landscape. We�…

It is acknowledged that empathy plays a critical role in the physician-patient relationship and
has a positive impact on health outcomes. However, as the field of empathy expands, the�…

Adverse nocebo responses can cause harm to patients and interfere with treatment
adherence and effects in both clinic practice and clinical trials. Nocebo responses refer to�…

This randomized controlled trial was performed to investigate whether placebo effects in
chronic low back pain could be harnessed ethically by adding open-label placebo (OLP)�…

To survive, organisms must effectively respond to the challenge of maintaining their
physiological integrity in the face of an ever-changing environment. Preserving this�…

Despite their ubiquitous presence, placebos and placebo effects retain an ambiguous and
unsettling presence in biomedicine. Specifically focused on chronic pain, this review�…